CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011713
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 816 
Protein Synonyms/Alias
  
Gene Name
 ZNF816 
Gene Synonyms/Alias
 ZNF816A 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
320YKCNECGKTFSEKSSubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 24 98 KRAB.
 ZN_FING 227 251 C2H2-type 1.
 ZN_FING 257 279 C2H2-type 2.
 ZN_FING 285 307 C2H2-type 3.
 ZN_FING 313 335 C2H2-type 4.
 ZN_FING 341 363 C2H2-type 5.
 ZN_FING 369 391 C2H2-type 6.
 ZN_FING 397 419 C2H2-type 7.
 ZN_FING 425 447 C2H2-type 8.
 ZN_FING 453 475 C2H2-type 9.
 ZN_FING 481 503 C2H2-type 10.
 ZN_FING 509 531 C2H2-type 11.
 ZN_FING 537 559 C2H2-type 12.
 ZN_FING 565 587 C2H2-type 13.
 ZN_FING 593 615 C2H2-type 14.
 ZN_FING 621 643 C2H2-type 15.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 651 AA 
Protein Sequence
MLREEATKKS KEKEPGMALP QGRLTFRDVA IEFSLEEWKC LNPAQRALYR AVMLENYRNL 60
EFVDSSLKSM MEFSSTRHSI TGEVIHTGTL QRHKSHHIGD FCFPEMKKDI HHFEFQWQEV 120
ERNGHEAPMT KIKKLTGSTD RSDHRHAGNK PIKDQLGLSF HSHLPELHMF QTKGKISNQL 180
DKSIGASSAS ESQRISCRLK THISNKYGKN FLHSSFTQIQ EICMREKPCQ SNECGKAFNY 240
SSLLRRHHIT HSREREYKCD VCGKIFNQKQ YIVYHHRCHT GEKTYKCNEC GKTFTQMSSL 300
VCHRRLHTGE KPYKCNECGK TFSEKSSLRC HRRLHTGEKP YKCNECGKTF GRNSALVIHK 360
AIHTGEKPYK CNECGKTFSQ KSSLQCHHIL HTGEKPYKCE ECDNVYIRRS HLERHRKIHT 420
GEGSYKCKVC DKVFRSDSYL AEHQRVHTGE KPYKCNKCGR SFSRKSSLQY HHTLHTGEKP 480
YTCNECGKVF SRRENLARHH RLHAGEKPYK CEECDKVFSR RSHLERHRRI HTGEKPYKCK 540
VCDKAFRSDS CLANHTRVHT GEKPYKCNKC AKVFNQKGIL AQHQRVHTGE KPYKCNECGK 600
VFNQKASLAK HQRVHTAEKP YKCNECGKAF TGQSTLIHHQ AIHGCRETLQ M 651 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS