UniProt Accession

 COX4_YEAST; P04037; A2TBN6; D6VTW7 

Genbank Protein ID

 X01418; X91489; Z72709; EF123139; Y00152; BK006941 

Genbank Nucleotide ID

 CAA25665.1; CAA62787.1; CAA96899.1; ABM97483.1; CAA68347.1; DAA07928.1 

Protein Name

 Cytochrome c oxidase subunit 4, mitochondrial 

Protein Synonyms/Alias

 Cytochrome c oxidase polypeptide IV 

Gene Name

 COX4 

Gene Synonyms/Alias

 YGL187C; G1362 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
32	LQQKPVVKTAQNLAE	acetylation	[1]
84	GIDVFDTKPLDSSRK	acetylation	[1]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

  

Sequence Annotation

 METAL 111 111 Zinc (Potential).
 METAL 134 134 Zinc (Potential).
 METAL 137 137 Zinc (Potential).
 MOD_RES 55 55 Phosphothreonine.  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; Phosphoprotein; Reference proteome; Transit peptide; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 155 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005758; C:mitochondrial intermembrane space; TAS:Reactome.
 GO:0005751; C:mitochondrial respiratory chain complex IV; IPI:SGD.
 GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IDA:SGD.
 GO:0009060; P:aerobic respiration; IPI:SGD.
 GO:0006123; P:mitochondrial electron transport, cytochrome c to oxygen; IDA:SGD. 

Interpro

 IPR002124; Cyt_c_oxidase_su5b.
 IPR020893; Cyt_c_oxidase_su5b_Zn_BS. 

Pfam

 PF01215; COX5B 

SMART

  

PROSITE

 PS00848; COX5B_1
 PS51359; COX5B_2 

PRINTS