| Tag | Content |
|---|
| CPLM ID | CPLM-018516 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L |
Protein Synonyms/Alias | PCAF-associated factor 65 beta; PAF65-beta |
Gene Name | Taf5l |
Gene Synonyms/Alias | Paf65b |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 481 | LSFSPNGKYLASAGE | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex (By similarity). |
Sequence Annotation | REPEAT 266 305 WD 1.
REPEAT 340 379 WD 2.
REPEAT 382 421 WD 3.
REPEAT 424 463 WD 4.
REPEAT 466 505 WD 5.
REPEAT 508 547 WD 6. |
Keyword | Complete proteome; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 589 AA |
Protein Sequence | MKRVRTEQVQ VAVSCYLKRR QYVDSEGPLK QGLRLSQTPE EMAANLTVQS ESGCANAVSA 60
APCQAEPQQY EVQFGRLRSF LTDSDSQYSR EVMPLLYPLF VYLHLNLVQS GPKSTVESFY 120
SRFHGMFLQN ASQKDVIEQL QTTQTIQDIL SNFQLRAFLD NKYVVRLQED SYNYLIRYLQ 180
SDNNTALCKV LAVHIHLDVQ PAKRTDYQLY ASGGSSRTEN SSLEPPEVPS PILQNEAALE 240
VLQESIKRVK DGPPSLTTIC FYAFYNTEQL LNTAEISSDS KLLAAGFDNS CIKLWSLRSK 300
KLKSEPHHVD TSRIRLACDT LEEEENEEDN TGTEMKILRG HCGPVYSTRF LADSSGLLSC 360
SEDMSIRYWD LGSFTNTVLY QGHAYPVWDV DISPFSLYFA SGSHDRTARL WSFDRTYPLR 420
IYAGHLADVD CVKFHPNSNY LATGSTDKTV RLWSAQQGNS VRLFTGHRGP VLSLSFSPNG 480
KYLASAGEDQ RLKLWDLASG TLFKELRGHT DSITSLAFSP DSGLIASASM DNSVRVWDIR 540
STCCNTPADG SSGELVGVYT GQMSNVLSVQ FMACNLLLVT GITQENQEH 589 |
Gene Ontology | GO:0030914; C:STAGA complex; IEA:Compara. GO:0033276; C:transcription factor TFTC complex; IEA:Compara. GO:0004402; F:histone acetyltransferase activity; IEA:Compara. GO:0003713; F:transcription coactivator activity; IEA:Compara. GO:0043966; P:histone H3 acetylation; IEA:Compara. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
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