CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034117
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Septin-2 
Protein Synonyms/Alias
  
Gene Name
 Sept2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
183NIVPVIAKADTLTLKacetylation[1]
183NIVPVIAKADTLTLKubiquitination[2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 213 AA 
Protein Sequence
MSKQQPTQFI NPETPGYVGF ANLPNQVHRK SVKKGFEFTL MVVGESGLGK STLINSLFLT 60
DLYPERIIPG AAEKIERTVQ IEASTVEIEE RGVKLRLTVV DTPGYGDAIN CRDCFKTIIS 120
YIDEQFERYL HDESGLNRRH IIDNRVHCCF YFISPFGHGL KPLDVAFMKA IHNKVNIVPV 180
IAKADTLTLK ERERLKKRIL DEIEEHSIKI YHL 213 
Gene Ontology
 GO:0015629; C:actin cytoskeleton; TAS:MGI.
 GO:0005938; C:cell cortex; TAS:MGI.
 GO:0042995; C:cell projection; IDA:MGI.
 GO:0009986; C:cell surface; IDA:MGI.
 GO:0000145; C:exocyst; IEA:Compara.
 GO:0030496; C:midbody; TAS:MGI.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara.
 GO:0005886; C:plasma membrane; IDA:MGI.
 GO:0031105; C:septin complex; IEA:InterPro.
 GO:0005876; C:spindle microtubule; TAS:MGI.
 GO:0045202; C:synapse; IDA:MGI.
 GO:0030234; F:enzyme regulator activity; IDA:MGI.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0042802; F:identical protein binding; TAS:MGI.
 GO:0032947; F:protein complex scaffold; IDA:MGI.
 GO:0007049; P:cell cycle; IEA:InterPro.
 GO:0031175; P:neuron projection development; IEA:Compara.
 GO:0051258; P:protein polymerization; TAS:MGI.
 GO:0002036; P:regulation of L-glutamate transport; IDA:MGI.
 GO:0032880; P:regulation of protein localization; IDA:MGI. 
Interpro
 IPR000038; Cell_div_GTP-bd.
 IPR027417; P-loop_NTPase.
 IPR016491; Septin.
 IPR008113; Septin2. 
Pfam
 PF00735; Septin 
SMART
  
PROSITE
  
PRINTS
 PR01740; SEPTIN2.