CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006823
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Menaquinone-specific isochorismate synthase 
Protein Synonyms/Alias
 Isochorismate mutase 
Gene Name
 menF 
Gene Synonyms/Alias
 yfbA; b2265; JW2260 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
420EWQEIDNKAAGLRTLacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
  
Sequence Annotation
  
Keyword
 3D-structure; Complete proteome; Isomerase; Menaquinone biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 431 AA 
Protein Sequence
MQSLTTALEN LLRHLSQEIP ATPGIRVIDI PFPLKDAFDA LSWLASQQTY PQFYWQQRNG 60
DEEAVVLGAI TRFTSLDQAQ RFLRQHPEHA DLRIWGLNAF DPSQGNLLLP RLEWRRCGGK 120
ATLRLTLFSE SSLQHDAIQA KEFIATLVSI KPLPGLHLTT TREQHWPDKT GWTQLIELAT 180
KTIAEGELDK VVLARATDLH FASPVNAAAM MAASRRLNLN CYHFYMAFDG ENAFLGSSPE 240
RLWRRRDKAL RTEALAGTVA NNPDDKQAQQ LGEWLMADDK NQRENMLVVE DICQRLQADT 300
QTLDVLPPQV LRLRKVQHLR RCIWTSLNKA DDVICLHQLQ PTAAVAGLPR DLARQFIARH 360
EPFTREWYAG SAGYLSLQQS EFCVSLRSAK ISGNVVRLYA GAGIVRGSDP EQEWQEIDNK 420
AAGLRTLLQM E 431 
Gene Ontology
 GO:0008909; F:isochorismate synthase activity; IDA:EcoCyc.
 GO:0000287; F:magnesium ion binding; IDA:EcoCyc.
 GO:0009234; P:menaquinone biosynthetic process; IMP:EcoCyc. 
Interpro
 IPR005801; ADC_synthase.
 IPR015890; Chorismate-bd_C.
 IPR004561; IsoChor_synthase. 
Pfam
 PF00425; Chorismate_bind 
SMART
  
PROSITE
  
PRINTS