CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006022
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Carcinoembryonic antigen-related cell adhesion molecule 1 
Protein Synonyms/Alias
 Biliary glycoprotein 1; BGP-1; Biliary glycoprotein D; MHVR1; Murine hepatitis virus receptor; MHV-R; CD66a 
Gene Name
 Ceacam1 
Gene Synonyms/Alias
 Bgp; Bgp1; Bgpd 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
519ETVYSEVKKK*****ubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Unknown. In case of murine coronavirus (MHV) infection, serves as receptor for MHV S1 spike glycoprotein. 
Sequence Annotation
 DOMAIN 35 142 Ig-like V-type.
 DOMAIN 147 234 Ig-like C2-type 1.
 DOMAIN 239 319 Ig-like C2-type 2.
 DOMAIN 323 411 Ig-like C2-type 3.
 CARBOHYD 71 71 N-linked (GlcNAc...).
 CARBOHYD 89 89 N-linked (GlcNAc...).
 CARBOHYD 104 104 N-linked (GlcNAc...).
 CARBOHYD 148 148 N-linked (GlcNAc...) (Potential).
 CARBOHYD 152 152 N-linked (GlcNAc...) (Potential).
 CARBOHYD 199 199 N-linked (GlcNAc...) (Potential).
 CARBOHYD 206 206 N-linked (GlcNAc...).
 CARBOHYD 210 210 N-linked (GlcNAc...) (Potential).
 CARBOHYD 226 226 N-linked (GlcNAc...) (Potential).
 CARBOHYD 258 258 N-linked (GlcNAc...) (Potential).
 CARBOHYD 290 290 N-linked (GlcNAc...) (Potential).
 CARBOHYD 294 294 N-linked (GlcNAc...) (Potential).
 CARBOHYD 304 304 N-linked (GlcNAc...) (Potential).
 CARBOHYD 317 317 N-linked (GlcNAc...).
 CARBOHYD 333 333 N-linked (GlcNAc...).
 CARBOHYD 375 375 N-linked (GlcNAc...).
 CARBOHYD 376 376 N-linked (GlcNAc...); atypical.
 DISULFID 167 217 Probable.
 DISULFID 261 301 Probable.
 DISULFID 346 394  
Keyword
 3D-structure; Alternative splicing; Cell membrane; Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Host cell receptor for virus entry; Host-virus interaction; Immunoglobulin domain; Membrane; Receptor; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 521 AA 
Protein Sequence
MELASAHLHK GQVPWGGLLL TASLLASWSP ATTAEVTIEA VPPQVAEDNN VLLLVHNLPL 60
ALGAFAWYKG NTTAIDKEIA RFVPNSNMNF TGQAYSGREI IYSNGSLLFQ MITMKDMGVY 120
TLDMTDENYR RTQATVRFHV HPILLKPNIT SNNSNPVEGD DSVSLTCDSY TDPDNINYLW 180
SRNGESLSEG DRLKLSEGNR TLTLLNVTRN DTGPYVCETR NPVSVNRSDP FSLNIIYGPD 240
TPIISPSDIY LHPGSNLNLS CHAASNPPAQ YFWLINEKPH ASSQELFIPN ITTNNSGTYT 300
CFVNNSVTGL SRTTVKNITV LEPVTQPFLQ VTNTTVKELD SVTLTCLSND IGANIQWLFN 360
SQSLQLTERM TLSQNNSILR IDPIKREDAG EYQCEISNPV SVRRSNSIKL DIIFDPTQGG 420
LSDGAIAGIV IGVVAGVALI AGLAYFLYSR KSGGGSDQRD LTEHKPSTSN HNLAPSDNSP 480
NKVDDVAYTV LNFNSQQPNR PTSAPSSPRA TETVYSEVKK K 521 
Gene Ontology
 GO:0060170; C:cilium membrane; IDA:MGI.
 GO:0016021; C:integral to membrane; ISO:MGI.
 GO:0043406; P:positive regulation of MAP kinase activity; ISO:MGI.
 GO:0019048; P:virus-host interaction; IEA:UniProtKB-KW. 
Interpro
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003598; Ig_sub2.
 IPR013106; Ig_V-set.
 IPR013151; Immunoglobulin. 
Pfam
 PF00047; ig
 PF07686; V-set 
SMART
 SM00408; IGc2 
PROSITE
 PS50835; IG_LIKE 
PRINTS