CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029448
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 SET domain-containing protein 4 
Protein Synonyms/Alias
  
Gene Name
 SETD4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
20RKWLKARKFQDSNLAubiquitination[1]
103AGHRSLWKPYLEILPubiquitination[1, 2, 3]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 283 AA 
Protein Sequence
MNESHKSEFI ELRKWLKARK FQDSNLAPAC FPGTGRGLMS QTSLQEGQMI ISLPESCLLT 60
TDTVIRSYLG AYITKWKPPP SPLLALCTFL VSEKHAGHRS LWKPYLEILP KAYTCPVCLE 120
PEVVNLLPKS LKAKAEEQRA HVQEFFASSR DFFSSLQPLF AEAVDSIFSY SALLWAWCTV 180
NTRAVYLRPR QRECLSAEPD TCALAPYLDL LNHSPHVQVK AAFNEETHSY EIRTTSRWRK 240
HEEVFICYGP HDNQRLFLEY GFVSVHNPHA CVYVSRGWNQ LCS 283 
Gene Ontology
  
Interpro
 IPR001214; SET_dom. 
Pfam
 PF00856; SET 
SMART
  
PROSITE
  
PRINTS