| Tag | Content |
|---|
| CPLM ID | CPLM-007354 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Quinidine resistance protein 2 |
Protein Synonyms/Alias | |
Gene Name | QDR2 |
Gene Synonyms/Alias | YIL121W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 32 | YNRETADKLALTRTE | ubiquitination | [1] | | 42 | LTRTESVKPEPEITA | ubiquitination | [1] | | 253 | GNGSVTPKSYLNRAP | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Multidrug resistance transporter involved in resistance and adaptation to quinidine and to the herbicide barban (4-chloro- 2-butynyl [3-chlorophenyl] carbamate). Implicated in potassium uptake. |
Sequence Annotation | MOD_RES 21 21 Phosphoserine.
MOD_RES 38 38 Phosphothreonine.
MOD_RES 40 40 Phosphoserine. |
Keyword | Cell membrane; Complete proteome; Ion transport; Membrane; Phosphoprotein; Potassium; Potassium transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 542 AA |
Protein Sequence | MAGATSSIIR ENDFEDELAE SMQSYNRETA DKLALTRTES VKPEPEITAP PHSRFSRSFK 60
TVLIAQCAFT GFFSTIAGAI YYPVLSVIER KFDIDEELVN VTVVVYFVFQ GLAPTFMGGF 120
ADSLGRRPVV LVAIVIYFGA CIGLACAQTY AQIIVLRCLQ AAGISPVIAI NSGIMGDVTT 180
RAERGGYVGY VAGFQVLGSA FGALIGAGLS SRWGWRAIFW FLAIGSGICF LASFLILPET 240
KRNISGNGSV TPKSYLNRAP ILVLPTVRKS LHLDNPDYET LELPTQLNLL APFKILKAYE 300
ICILMLVAGL QFAMYTTHLT ALSTALSKQY HLTVAKVGLC YLPSGICTLC SIVIAGRYLN 360
WNYRRRLKYY QNWLGKKRSK LLEEHDNDLN LVQRIIENDP KYTFNIFKAR LQPAFVTLLL 420
SSSGFCAYGW CITVKAPLAA VLCMSGFASL FSNCILTFST TLIVDLFPTK TSTATGCLNL 480
FRCILSAVFI AALSKMVEKM KFGGVFTFLG ALTSSSSILL FILLRKGKEL AFKRKKQELG 540
VN 542 |
Gene Ontology | GO:0005887; C:integral to plasma membrane; IDA:SGD. GO:0008324; F:cation transmembrane transporter activity; IMP:SGD. GO:0015238; F:drug transmembrane transporter activity; IMP:SGD. GO:0060003; P:copper ion export; IMP:SGD. GO:0010107; P:potassium ion import; IMP:SGD. |
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Pfam | |
SMART | |
PROSITE | |
PRINTS | |