UniProt Accession

 PP14B_MOUSE; Q62084; Q640Q7 

Genbank Protein ID

 X97490; BC082545; BC125650; BC125654 

Genbank Nucleotide ID

 CAA66121.1; AAH82545.2; AAI25651.1; AAI25655.1 

Protein Name

 Protein phosphatase 1 regulatory subunit 14B 

Protein Synonyms/Alias

 Phosphatase holoenzyme inhibitor 1; PHI-1; Phospholipase C-beta-3 neighbouring gene protein 

Gene Name

 Ppp1r14b 

Gene Synonyms/Alias

 Png 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
114	DTRAARVKELLVDCY	acetylation	[1]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

 Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated. 

Sequence Annotation

 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 32 32 Phosphoserine (By similarity).
 MOD_RES 57 57 Phosphothreonine.  

Keyword

 Acetylation; Coiled coil; Complete proteome; Cytoplasm; Phosphoprotein; Protein phosphatase inhibitor; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 147 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
 GO:0008599; F:protein phosphatase type 1 regulator activity; IEA:Compara.
 GO:0042325; P:regulation of phosphorylation; IEA:InterPro. 

Interpro

 IPR008025; PP1_inhibitor. 

Pfam

 PF05361; PP1_inhibitor 

SMART

  

PROSITE

  

PRINTS