CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016404
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Synaptoporin 
Protein Synonyms/Alias
  
Gene Name
 Synpr 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
217YLSDPMEKHSSSYNQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By similarity). 
Sequence Annotation
 DOMAIN 1 202 MARVEL.
 REPEAT 210 214 1.
 REPEAT 222 226 2.
 REPEAT 227 231 3.
 REPEAT 232 236 4.
 REPEAT 238 242 5.
 REGION 210 242 5 X approximate repeats.
 CARBOHYD 33 33 N-linked (GlcNAc...) (Potential).
 CARBOHYD 38 38 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; Cell junction; Complete proteome; Cytoplasmic vesicle; Direct protein sequencing; Glycoprotein; Membrane; Reference proteome; Repeat; Synapse; Synaptosome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 265 AA 
Protein Sequence
MCMVIFAPLF AMFAFATCGG YSGGLRLSVD CVNKTESNLS IDIAFAYPFR LQQVTFEVPT 60
CEGKEQQKLA LVGDSSSSAE FFVTVAVFAF LYSLAATVVY IFFQNKYREN NRGPLIDFIV 120
TVVFSFLWLV GSSAWAKGLS DVKVATDPKE VLLLMSACKQ PSNKCMAVHS PVMSSLNTSV 180
VFGFLNFILW AGNIWFVFKE TGWHSSGQRY LSDPMEKHSS SYNQGRYNQE SYGSSGGYSQ 240
QANLGPTSDE FGQQPSGPTS FNNQI 265 
Gene Ontology
 GO:0030054; C:cell junction; IEA:UniProtKB-KW.
 GO:0030285; C:integral to synaptic vesicle membrane; TAS:MGI.
 GO:0043005; C:neuron projection; IEA:UniProtKB-SubCell.
 GO:0005215; F:transporter activity; IEA:InterPro. 
Interpro
 IPR008253; Marvel.
 IPR021128; MARVEL-like_dom.
 IPR001285; Synaptophysin/porin. 
Pfam
 PF01284; MARVEL 
SMART
  
PROSITE
 PS51225; MARVEL
 PS00604; SYNAPTOP 
PRINTS
 PR00220; SYNAPTOPHYSN.