Tag | Content |
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CPLM ID | CPLM-027068 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Dynein heavy chain at 62B |
Protein Synonyms/Alias | |
Gene Name | Dhc62B |
Gene Synonyms/Alias | CG15804; Dmel_CG15804 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
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1625 | WTDGLVAKIFRDFAM | acetylation | [1] |
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Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | |
Sequence Annotation | |
Keyword | ATP-binding; Complete proteome; Hydrolase; Nucleotide-binding; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 3964 AA |
Protein Sequence | MYTKKLERMH RPASDITKYD NEPYMKNPLL KFRISEVHER RHYQFLKQKA ADVKVRVARQ 60 QWQPEPDMRL LPQSHYEDNL RREVRKIVVP PMLRRTEAKI LSFASERLKN KYPELVQAYM 120 HDVHEEFNRL MKVYSMKNIL RHPEFSDEDP AQFELPRPDI GFRRPGRTQN YSNFLENRRR 180 IAQKLLILQL PLRAILNISV GELPKLACIF NYVLATGAMQ QQLGLGGREA LSYKFYHKYI 240 QNQLDKVNTF LRWTWYPKIV QVLRKLMRKR VMPMSTWKRS WNAMEALMNR EMTNMKIRTF 300 EEMYRMCSHP RTMPMMRMSL EWSEFSSDLD TRPNAWSILR TFAEIATEIS MVGYRMEPLQ 360 PQVQTLTSMA AYAKVNDYLK IEMNDNFLKD VIDKVQNIIL RTYQEVIQYV EGFRDKYYAL 420 YSWQERDALN QFLSEPHEFE EYFARIDMYY GFIQMLRSEP ATEYFVMAVI HNEPAIFGLR 480 TLAENLIHEI TTIIIREHIK AEVDICDEFE KIKYRALEIP KSTEELLESA EYMIHVKKDK 540 IAELTDRIQY CLQVGTNIVE LTEMSKYHFD LTIKTINWIK DINDICDYNA SQQEQFKFTF 600 EEHLQEVIKK LNSDIDELLP KLTVIDDMSR PDKFRDSYII LQNFIDQLKT FDDYVAWINK 660 EEKLFKVALT EYPKLDIIKT FVYPFAELMK CCIEWQRYLS VWNDGPFEYL EPQFVERTTD 720 DYLKEFQKNQ KYYRVKIKQD LIDNPVCKFK GQTEDPDPAK HPVPLRLCTS MIQSIKDFTT 780 GVFIVNTMCN PALRKRHWKE MSEIAGFDVT PDAGTTLRKI LNSGLDPILD QFEIISIGAN 840 KELQLWNALQ AMIKEWETRV FPYGPYKETG VQILSSLDDI QALLDDHILK TLVMRGSAFM 900 KPCEEEVRAW YEKIMRVNET LDQWGKVQAN YLYLLPIFSS KDIVAQMPEE GRLFVIVEQT 960 YTRNMGLVLR QPLVMETAPV SGLLESLQKA NELLEDIATG VSNYLEKKRL YFPRFFFLAN 1020 DEMLEILSET KDPLRVLPHL SKCFEGINSL EFDAAKNVLA MISSDKETIE FIEQVSTAAA 1080 GGSVEKWLIG VEDEMLKAVR YQNELSFAHY PKVKRHEWVL EWPQMTVLAI SQVYWASRVH 1140 GCLRRTFGGN MTIMMNFFQE LSKELNDIVT LVRSPKISNL NRITIKSLIV IDVHAKDVSE 1200 DLIKNKVSSE FDFQWLAQMR YYWEDDKTWV RIINATVPFA NEYLGNSDRL VITPLTDRCY 1260 RTLVGAYQLH LNGAPEGPAG TGKTETTKDL AKALAVQCKV FNCSDGLDYK AMGKFFKGLA 1320 SCGAWACFDE FNRIELEVLS VVAQQILLII QAVRSNATKF MFEGTELTLN PACYVCITMN 1380 PGYAGRSELP DNLKVLFRSV AMMVPDYAMI GEISLYSYGF VDARKLAVKI VTTYRLCSEQ 1440 LSSQNHYDYG MRAVKTVLSA CGNIKKQYPD EVEDILLLRS LIDVNLPKFL SFDVPLFEGI 1500 ISDIFPGIKL PHIDYSLVES EFKRVCLEEV LEPAPSFLLK VIQTYEMIIV RHGFMLVGEP 1560 LAGKSKTLQV LAKVLSALKI KAPQKSNYFQ HVQMGIMNPK SITMNQLYGS FDPISYEWTD 1620 GLVAKIFRDF AMTPTPDRKW VIFDGPVDAV WIENMNTVLD DNKKLCLTSG EVITMSNEMS 1680 MVFEVMDLAQ ASPATVSRCG MIYMEPSTLG WRAFAKSWLK KADPRWADEE GVPYVMALMQ 1740 WLLPPCQTFV RRFCSQFIKP GEFNCMLTTF DLFDMQIAEA IEENPEDYQK YLQTYFQAAI 1800 LFALIWGVGG VLDTASREKF DVFLKKLWDT DPPPPEPLGK MEITPPTEGL LVDYVFLYKQ 1860 RGAWRYWPDL AKRMDVEETK TGVIVPTVDT ARYIHLLKMH VEHKKRMLLV GPTGTGKTVY 1920 VQNYLMNKLD KEVFETGFIT FTVMISANQC QDLLISKLQK WKRGIYGPPK GMQSVLFVDD 1980 MNMPVKEVYG AQPPLELLRQ FFDYGHVYDL KDSSKVYIHN VLIMAACGLP GGSRQDVYAR 2040 FLNHFNVYSI NTFSDDSMFR IFLNVALNGF RRAGHGQDVF VVTNQIVSAT QSIYKSVQSE 2100 IRATPSKSHY IFNLRDISRV VTGCTLVRKE SVSDKKIFVR VWYHEAMRVF YDRLVDDVDR 2160 KWMFDKLNEC LKANFKDKVE TVFERYCVQG PDEAVFTMEA ASNILFGVYF DEDSVPDERR 2220 YEEVPSVEVF LNLALTSLDD YNSTRRNKMD ITLFTFALQH LNRICRIISI QGASALIIGL 2280 GGSGRQSLTK LATNMVQTSF FQPEITKNYG ANDWHDDIKA ILKEAGGMNK HTTFLITENQ 2340 IKMELFLQDI DCLLNQGEVP NIFPIDEKQE VLEMVRLAAQ GGNRNIDVSA LQVFSFFVDR 2400 CKQKLHMILS FSPIGDALRT RVRLYPSLVN CCTIDWYDSW PEEALQMIAK MSLVDVNVPS 2460 EDIKLAIMDT CQYFHTTAAR STRAFCQMTG RHIYQTNASF IELIRSFQTL IERKQSETML 2520 AKMRYIGGLD TLAQAAAAIS IMQRDLNALQ PKLVALAESS RKMMLEINKE TLAASAAAEQ 2580 VKRDEEVASV QAEAAQVLKQ DCERDLAKAI PVLEDALAAL NTLKPADITL VKSMKNPPPV 2640 IKLVMAAVCV IKGIPPERIP DPASGKMVQD YWGPSKRLLG EMNFLPGLKE FDKDNIPTEI 2700 VKRIHKEFIP NKDFDPKVVA KASSAAKGLC QWIIAMMMYD EVAKVVAPKK AKLAGAEKEY 2760 ADTMEFLAQK RALALALEEK VALLNIELDK ANAEMQKTEE HAESCRNKLL RAEALIGGLG 2820 GEKSRWNKAA EDLQELYDHL PGDVLISCGI IAYLSAVNLQ YRSECVKDWF KKVTDLKIPC 2880 SSHYSITDVL GLEVTIQNWQ LDGLPNDEFS SENAIISANS SRYSLFIDPQ AQANNWLKNM 2940 ERKNRLNCVK FNQSNYMKVI AEALEYGTPV IIENVQEELE VPLDPILMRQ TFVQGGIKHI 3000 SLGESVVPVN PNFRLYMTCN LRNPHFLPET FNKVTVINFA LTQNALMDQL LSIVVAKERP 3060 DLQELRITLT TEAAANKGAL RDAENMILKT LSAGGDILEN EAAIQILADS KGLSKDIVEK 3120 QEAAKETVAK IEAFRLNYKP VAVHSSILYY SITDLPNIDP MYQFSLNWYI NLYMYSIETA 3180 NKSKDLPRRI KFLVDGFTRN LYNNVCRSIF EKDKLLYSFI LTARILLGTG QVEMRHFAHL 3240 VTNAKESTNI PPNPDPTWIT ETVWLNVLRL EELKELRGIV DHFKSHLHAW QAIYDHSSPE 3300 KQPLPPPWQD KTTAFEKIIV LKALRPDSVF LAVRLFIAES IGDQYVTPPE FDISKSYADS 3360 TALTPLVFIL SPGADPLGSL LAFAEKMGQE ETFQSISLGQ GQGPIATALI KNAQEMGYWV 3420 CLQNCHLAAS WMPYLEYLWE NMDTFNTTPN FRIWLTAYPT PQFPVTILQN GVKMTNEPPT 3480 GLKENLMRSY NSEPINDYEF YTGCAKQDRA FTRLLYGICF FHAVVQERRK YGPLGWNIAY 3540 GFNESDLQIS VLQLSMLLNQ YDHVPYDAIS YLTSECNYGG RVTDNWDRRL IVTILADFCN 3600 AQAVTDNRYR FASDDRYILP RKTEHREILR YLDENLPSLA PPEVYGLHAN SGITRDLQTT 3660 KTLLDSMILL LGSEAAGSAG AGVSVEQVIL DTIKQIEREM PADMDIEAAA EKYPVDYNES 3720 MNTVVVQEME RFLKLQKEIR TTCRDLAMGI KGIIVMTPDL ENVMTAMKFN RIPTKWMSKS 3780 YPCLKPLGSY VQDLYKRLNW LHDWHHHGKP PTFWLSGFFF TQAFLTGAMQ NFARKYKIPI 3840 DTLTFDYDVL KVETKTSPPD DGVYCNGLYL EGARWEWREN TLVEQFPKVL IYAMPVIFFR 3900 PVGLVDVVEG SRYRCPLYKT AERKGTLSTT GHSTNYVVPL LLNTHVKASH WVKRSVALIC 3960 QTSD 3964 |
Gene Ontology | GO:0030286; C:dynein complex; IEA:InterPro. GO:0005875; C:microtubule associated complex; ISS:FlyBase. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0042623; F:ATPase activity, coupled; ISS:FlyBase. GO:0003777; F:microtubule motor activity; IEA:InterPro. GO:0007018; P:microtubule-based movement; ISS:FlyBase. GO:2001019; P:positive regulation of retrograde axon cargo transport; IMP:FlyBase. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |