CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041777
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Similar to putative TRAF and TNF receptor associated protein, isoform CRA_c 
Protein Synonyms/Alias
 Tyrosyl-DNA phosphodiesterase 2 
Gene Name
 Tdp2 
Gene Synonyms/Alias
 LOC498749; rCG_45198 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
248AERINQLKTVFQKMQacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Receptor; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 366 AA 
Protein Sequence
MASGSSSDAA ESAEPAAAPA AAETEEDQVK RRRLQSLGFA LVTSCDTTVA STFLSENNWQ 60
TKKALSAFFE QPENDLARPH QPPTSSKSED YVDLTNEDAN DTTILETSPS GTPLEDSSTI 120
SFITWNIDGL DGCNLPERAR GVCSCLALYS PDVVFLQEVI PSYCAYLRKR ARTYNIITGN 180
EEGYFTAILL KKGRVKFKSQ EIIPFPNTKM MRNLLCVNVS LGGNEFCLMT SHLESTRKHS 240
AERINQLKTV FQKMQEATDS TTVIFAGDTN LRDQEVIKCG GLPDNVFDAW EFLGKPKHCR 300
YTWDTKANDN LRIPAACKHR FDRIFFRAEE GHLIPQSLDL IGLERLDCGR FPSDHWGLLC 360
TLNVVL 366 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0016605; C:PML body; IEA:Compara.
 GO:0070260; F:5'-tyrosyl-DNA phosphodiesterase activity; IEA:Compara.
 GO:0030145; F:manganese ion binding; IEA:Compara.
 GO:0003697; F:single-stranded DNA binding; IEA:Compara.
 GO:0036317; F:tyrosyl-RNA phosphodiesterase activity; IEA:Compara.
 GO:0006302; P:double-strand break repair; IEA:Compara. 
Interpro
 IPR005135; Endo/exonuclease/phosphatase. 
Pfam
 PF03372; Exo_endo_phos 
SMART
  
PROSITE
  
PRINTS