CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036443
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Transducin-like enhancer protein 3 
Protein Synonyms/Alias
  
Gene Name
 Tle3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
343GLRSMPGKPPGMDPIacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 767 AA 
Protein Sequence
MYPQGRHPAP HQPGQPGFKF TVAESCDRIK DEFQFLQAQY HSLKVEYDKL ANEKTEMQRH 60
YVMYYEMSYG LNIEMHKQTE IAKRLNTILA QIMPFLSQEH QQQVAQAVER AKQVTMTELN 120
AIIGQQQLQA QHLSHATHGP PVQLPPHPSG LQPPGIPPVT GSSSGLLALG ALGSQAHLAV 180
KDEKNHHELD HRERESSTNN SVSPSESLRA SEKHRGSADY SMEAKKRKAE EKDSLSRYDS 240
DGDKSDDLVV DVSNEDPATP RVSPAHSPPE NGLDKARGLK KDAPTSPASV ASSSSTPSSK 300
TKDLGHNDKS STPGLKSNTP TPRNDAPTPG TSTTPGLRSM PGKPPGMDPI GIMASALRTP 360
ITLTSSYPAP FAMMSHHEMN GSLTSPSAYA GLHNIPSQMS AAAAAAAAAY GRSPMVGFDP 420
HPPMRATGLP SSLASIPGGK PAYSFHVSAD GQMQPVPFPH DALAGPGIPR HARQINTLSH 480
GEVVCAVTIS NPTRHVYTGG KGCVKIWDIS QPGSKSPISQ LDCLNRDNYI RSCKLLPDGR 540
TLIVGGEAST LTIWDLASPT PRIKAELTSS APACYALAIS PDAKVCFSCC SDGNIAVWDL 600
HNQTLVRQFQ GHTDGASCID ISHDGTKLWT GGLDNTVRSW DLREGRQLQQ HDFTSQIFSL 660
GYCPTGEWLA VGMESSNVEV LHHTKPDKYQ LHLHESCVLS LKFAYCGKWF VSTGKDNLLN 720
AWRTPYGASI FQSKESSSVL SCDISADDKY IVTGSGDKKA TVYEVIY 767 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR005617; Groucho/TLE_N.
 IPR009146; Groucho_enhance.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF03920; TLE_N
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR01850; GROUCHOFAMLY.