CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040516
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tropomyosin 1, alpha, isoform CRA_c 
Protein Synonyms/Alias
 Tropomyosin alpha-1 chain 
Gene Name
 Tpm1 
Gene Synonyms/Alias
 rCG_56696 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
5***MDAIKKKMQMLKacetylation[1]
7*MDAIKKKMQMLKLDacetylation[1]
12KKKMQMLKLDKENALacetylation[1]
112RLATALQKLEEAEKAacetylation[1]
112RLATALQKLEEAEKAubiquitination[2]
118QKLEEAEKAADESERacetylation[1]
161IAEDADRKYEEVARKacetylation[1]
205KTVTNNLKSLEAQAEubiquitination[2]
213SLEAQAEKYSQKEDKacetylation[1]
217QAEKYSQKEDKYEEEacetylation[1]
220KYSQKEDKYEEEIKVacetylation[1]
233KVLSDKLKEAETRAEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
  
Sequence Annotation
  
Keyword
 Coiled coil; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 284 AA 
Protein Sequence
MDAIKKKMQM LKLDKENALD RAEQAEADKK AAEDRSKQLE EDISAKEKLL RASEDERDRV 60
LEELHKAEDS LLAADETAAK AEADVASLNR RIQLVEEELD RAQERLATAL QKLEEAEKAA 120
DESERGMKVI ESRAQKDEEK MEIQEIQLKE AKHIAEDADR KYEEVARKLV IIESDLERAE 180
ERAELSEGKC AELEEELKTV TNNLKSLEAQ AEKYSQKEDK YEEEIKVLSD KLKEAETRAE 240
FAERSVTKLE KSIDDLEEKV AHAKEENLSM HQMLDQTLLE LNNM 284 
Gene Ontology
  
Interpro
 IPR000533; Tropomyosin. 
Pfam
 PF00261; Tropomyosin 
SMART
  
PROSITE
 PS00326; TROPOMYOSIN 
PRINTS
 PR00194; TROPOMYOSIN.