| Tag | Content |
|---|
| CPLM ID | CPLM-015052 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Leucine--tRNA ligase |
Protein Synonyms/Alias | Leucyl-tRNA synthetase; LeuRS |
Gene Name | leuS |
Gene Synonyms/Alias | RPA0287 |
Created Date | July 27, 2013 |
Organism | Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) |
NCBI Taxa ID | 258594 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 18 | SEPKWQAKWDEAKIF | acetylation | [1] | | 293 | AFIDDCKKRGTAQAE | acetylation | [1] |
|
Reference | [1] System-wide studies of N-lysine acetylation in Rhodopseudomonas palustris reveal substrate specificity of protein acetyltransferases. Crosby HA, Pelletier DA, Hurst GB, Escalante-Semerena JC. J Biol Chem. 2012 May 4;287(19):15590-601. [ PMID: 22416131] |
Functional Description | |
Sequence Annotation | MOTIF 43 53 "HIGH" region.
MOTIF 632 636 "KMSKS" region.
BINDING 635 635 ATP (By similarity). |
Keyword | Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Cytoplasm; Ligase; Nucleotide-binding; Protein biosynthesis. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 876 AA |
Protein Sequence | MSNERYNARE SEPKWQAKWD EAKIFATRND DLRKKYYVLE MFPYPSGRIH MGHVRNYTMG 60
DVVARTMRAR GYNVLHPMGW DAFGLPAENA AIERKVAPKA WTYDNIAAMK KQLQTMGLSL 120
DWAREFATCD PSYYKHQQKM FLDFLKVGLV EREKRKLNWD PVDMTVLANE QVIDGRGWRS 180
GAVVELREMN QWVFKITKYA QELLDALDTL DRWPDKVRLM QRNWIGRSEG LMVRFALDSA 240
TTPAGETELK IFTTRPDTLF GAKFMAIAAD HPLAQAAAAK APKVAAFIDD CKKRGTAQAE 300
IDTAEKQGID TGIRAVHPFD PSWKLPVYVA NFVLMEYGTG AIFGCPAHDQ RDLDFVNKYQ 360
LGNTPVVCPE GQDPASFVIT DTAYDGEGRM INSRFLDGKT IAEAKEEVAK RLETEQLAGA 420
PVGARKVNFR LRDWGISRQR YWGCPIPIIH CPTCDVVPVP DADLPVVLPE DVSFDKPGNA 480
LDHHPTWKHV TCPKCGGKAV RETDTMDTFV DSSWYFARFT DPWNTEAPTT PDVVNRMMPV 540
DQYIGGVEHA ILHLLYSRFF TRAMKAAGHI DIQHDEPFAG LFTQGMVVHE TYRKADGHFA 600
SPAEISITVE GDTRRATLLD GGSPVEIGPI EKMSKSKRNT VDPDDIIGTY GADTARWFML 660
SDSPPDRDVI WSEEGVKGAS RFVQRLWRMV NDAAPIAASA PAERPASFGA DALTLRKAAH 720
GALDKVLSGI ERLAFNVSLA HIREFSNTLG DALARSQTPS PDLAWAIRES TVILVQLFHP 780
MMPHLAEECW TVLGQTGLVS EALWPPIEQD LLVEDSITLP VQVNGKKRGD VTVPRDAPTS 840
EIEAAVLALD TVKQALGGKP VRKVIVVPQR IVNVVG 876 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0002161; F:aminoacyl-tRNA editing activity; IEA:InterPro. GO:0005524; F:ATP binding; IEA:HAMAP. GO:0004823; F:leucine-tRNA ligase activity; IEA:HAMAP. GO:0006429; P:leucyl-tRNA aminoacylation; IEA:HAMAP. GO:0006450; P:regulation of translational fidelity; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |