CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025678
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 mRNA decapping enzyme variant 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
128PRQLNDVKTTVVYPAubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 337 AA 
Protein Sequence
MADAAPQLGK RKRELDVEEA HAASTEEKEA GVGNGTCAPV RLPFSGFRLQ KVLRESARDK 60
IIFLHGKVNE ASGDGDGEDA VVILEKTPFQ VEQVAQLLTG SPELQLQFSN DIYSTYHLFP 120
PRQLNDVKTT VVYPATEKHL QKYLRQDLRL IRETGDDYRN ITLPHLESQS LSIQWVYNIL 180
DKKAEADRIV FENPDPSDGF VLIPDLKWNQ QQLDDLYLIA ICHRRGIRSL RDLTPEHLPL 240
LRNNLHQGQE AILQRYRMKG DHLRVYLHYL PSYYHLHVHF TALGFEAPGS GVERAHLLAE 300
VIENLECDPR HYQQRTLTFA LRADDPLLKL LQEAQQS 337 
Gene Ontology
 GO:0016787; F:hydrolase activity; IEA:InterPro.
 GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IEA:InterPro. 
Interpro
 IPR008594; DcpS/DCS2.
 IPR019808; Histidine_triad_CS.
 IPR011146; HIT-like.
 IPR011145; Scavenger_mRNA_decap_enz_N. 
Pfam
 PF05652; DcpS 
SMART
  
PROSITE
 PS00892; HIT_1 
PRINTS