CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008760
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cell wall integrity and stress response component 2 
Protein Synonyms/Alias
  
Gene Name
 WSC2 
Gene Synonyms/Alias
 YNL283C; N0583 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
400RNNTALSKNTASTFAubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
  
Sequence Annotation
 DOMAIN 25 118 WSC.
 MOD_RES 402 402 Phosphothreonine.
 MOD_RES 455 455 Phosphoserine.
 MOD_RES 458 458 Phosphoserine.  
Keyword
 Cell membrane; Cell wall biogenesis/degradation; Complete proteome; Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 503 AA 
Protein Sequence
MHLDLIHKSF ILVWLIYIRA ALADQFTYKA CYSASDIRKL GLTYKGVYEY QSVSYCQNEC 60
PGQAVVALFN GTGCYCGGSV AQLQSLTQVD SSKCDVSCAG WPYQNCGGSS AMNVYINNAA 120
STADSTSSTA TSTSTTSSSS TSVSSKTSTK LDTKTSTSSS ATHSSSSSST TSTTTSSSET 180
TTSSSSSSSS SSTSTTSTTS TTSSTTSTSS SPSTTSSSTS ASSSSETSST QATSSSTTST 240
SSSTSTATVT STPSSTSIGT STHYTTRVVT QSVVSQANQQ ASTIFTTRTS VYATVSSTSS 300
STSSLLNGKS SSSKSKGLSG GAIAGVVVGV VCGTVALLAL ALFFFVWKKR RQSSQHVDLE 360
ETKQYQPYSL GDADANPVIP PSASSTNWHI PSRNNTALSK NTASTFATYD LPTRAPGGRD 420
SIITGDAHNI SKRSHFPSVV YEEPPSIYNG NQRFSATSLP DMMEERQLHI VNPDNVSSNI 480
GSNVSDGDDD YDDAKDSNNS SLR 503 
Gene Ontology
 GO:0005933; C:cellular bud; IDA:SGD.
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0043332; C:mating projection tip; IDA:SGD.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0004888; F:transmembrane signaling receptor activity; IGI:SGD.
 GO:0031505; P:fungal-type cell wall organization; IMP:SGD.
 GO:0009408; P:response to heat; IGI:SGD.
 GO:0007266; P:Rho protein signal transduction; IGI:SGD. 
Interpro
 IPR002889; WSC_carb-bd.
 IPR013994; WSC_carb-bd_subgr. 
Pfam
 PF01822; WSC 
SMART
 SM00321; WSC 
PROSITE
 PS51212; WSC 
PRINTS