| Tag | Content |
|---|
| CPLM ID | CPLM-022104 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | 1-acyl-sn-glycerol-3-phosphate acyltransferase delta |
Protein Synonyms/Alias | 1-acylglycerol-3-phosphate O-acyltransferase 4; 1-AGP acyltransferase 4; 1-AGPAT 4; Lysophosphatidic acid acyltransferase delta; LPAAT-delta |
Gene Name | AGPAT4 |
Gene Synonyms/Alias | UNQ499/PRO1016 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 87 | RAYLKYGKENAIVVL | ubiquitination | [1] | | 281 | LHKLYQEKDAFQEEY | ubiquitination | [1] |
|
Reference | [1] Systematic and quantitative assessment of the ubiquitin-modified proteome. Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP. Mol Cell. 2011 Oct 21;44(2):325-40. [ PMID: 21906983] |
Functional Description | Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity). |
Sequence Annotation | MOTIF 96 101 HXXXXD motif. |
Keyword | Acyltransferase; Complete proteome; Lipid biosynthesis; Lipid metabolism; Membrane; Phospholipid biosynthesis; Phospholipid metabolism; Reference proteome; Transferase; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 378 AA |
Protein Sequence | MDLAGLLKSQ FLCHLVFCYV FIASGLIINT IQLFTLLLWP INKQLFRKIN CRLSYCISSQ 60
LVMLLEWWSG TECTIFTDPR AYLKYGKENA IVVLNHKFEI DFLCGWSLSE RFGLLGGSKV 120
LAKKELAYVP IIGWMWYFTE MVFCSRKWEQ DRKTVATSLQ HLRDYPEKYF FLIHCEGTRF 180
TEKKHEISMQ VARAKGLPRL KHHLLPRTKG FAITVRSLRN VVSAVYDCTL NFRNNENPTL 240
LGVLNGKKYH ADLYVRRIPL EDIPEDDDEC SAWLHKLYQE KDAFQEEYYR TGTFPETPMV 300
PPRRPWTLVN WLFWASLVLY PFFQFLVSMI RSGSSLTLAS FILVFFVASV GVRWMIGVTE 360
IDKGSAYGNS DSKQKLND 378 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0003841; F:1-acylglycerol-3-phosphate O-acyltransferase activity; NAS:UniProtKB. GO:0016024; P:CDP-diacylglycerol biosynthetic process; IEA:UniProtKB-UniPathway. GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome. GO:0044281; P:small molecule metabolic process; TAS:Reactome. GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome. |
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