CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010662
UniProt Accession
Genbank Protein ID
 X97831 
Genbank Nucleotide ID
Protein Name
 Mitochondrial carnitine/acylcarnitine carrier protein 
Protein Synonyms/Alias
 Carnitine/acylcarnitine translocase; CAC; Solute carrier family 25 member 20 
Gene Name
 Slc25a20 
Gene Synonyms/Alias
 Cact 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
170FGIRGFYKGTALTLMacetylation[1]
244FQTAPPGKYPNGFRDacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. 
Sequence Annotation
 REPEAT 8 99 Solcar 1.
 REPEAT 108 196 Solcar 2.
 REPEAT 207 293 Solcar 3.
 MOD_RES 148 148 N6-acetyllysine (By similarity).
 MOD_RES 244 244 N6-acetyllysine (By similarity).  
Keyword
 3D-structure; Acetylation; Complete proteome; Direct protein sequencing; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 301 AA 
Protein Sequence
MAEEPKPISP LKNLLAGGFG GVCLVFVGHP LDTVKVRLQT QPPSLPGQPP MYSGTIDCFR 60
KTLFREGITG LYRGMAAPII GVTPMFAVCF FGFGLGKRLQ QKSPEDELTY PQLFTAGMLS 120
GVFTTGIMTP GERIKCLLQI QASSGKNKYS GTLDCAKKLY QEFGIRGFYK GTALTLMRDV 180
PASGMYFMTY EWLKNLFTPQ GKSVHDLSVP RVLVAGGFRG IFNWVVAIPP DVLKSRFQTA 240
PPGKYPNGFR DVLRELIREE GVTSLYKGFN AVMIRAFPAN AACFLGFEIP MKILNWIAPN 300
L 301 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005743; C:mitochondrial inner membrane; TAS:RGD.
 GO:0006810; P:transport; NAS:RGD. 
Interpro
 IPR018108; Mitochondrial_sb/sol_carrier.
 IPR023395; Mt_carrier_dom. 
Pfam
 PF00153; Mito_carr 
SMART
  
PROSITE
 PS50920; SOLCAR 
PRINTS