CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016567
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tetratricopeptide repeat protein 26 
Protein Synonyms/Alias
 TPR repeat protein 26 
Gene Name
 Ttc26 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
482GQFYYSAKAFDVLERubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May play a critical role in ciliogenesis and normal cilia function. 
Sequence Annotation
 REPEAT 57 90 TPR 1.
 REPEAT 92 125 TPR 2.
 REPEAT 151 184 TPR 3.
 REPEAT 468 501 TPR 4.  
Keyword
 Cell projection; Cilium; Cilium biogenesis/degradation; Complete proteome; Reference proteome; Repeat; TPR repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 554 AA 
Protein Sequence
MMLSRAKPAV GGESPHTDKR KKKGRKIPKL EDLLSQRDFT GAITLLEFKR HVGEQEDDTN 60
LWIGYCAFHL GDYKRALEEY ENATKEENCN PEVWVNLACT YFFLGMYKQA EAAGFKAPKS 120
RLQNRLLFHL AHKFNDEKKL MNFHQNLQDI KEDQLSLASI HYMRSHYQEA IDIYKRILLD 180
NREYLALNVY VALCYYKLDY YDVSQEVLAV YLQQIPDSTI ALNLKACNHF RLYNGKAAEA 240
ELKSLMDNAS SPFEFAKELI RHNLVVFRGG EGALQVLPPL VDVIPEARLN LVIYYLRQDD 300
VQEAYNLIKD LEPTTPQEYI LKGVVNAALG QEMGSRDHMK IAQQFFQLVG GSASECDTIP 360
GRQCMASCFF LLKQFDDVLI YLNSFKSYFY NDDIFNFNYA QAKAATGNTS EGEEVFLLIQ 420
SEKLKNDYIY LSWLARCYIM NKKPRLAWEL YLKMETSGES FSLLQLIAND CYKMGQFYYS 480
AKAFDVLERL DPNPEYWEGK RGACVGIFQM ILAGREPKET LREVLHLLRS TGNTQVEYII 540
RIMKKWAKEN RVPI 554 
Gene Ontology
 GO:0036064; C:cilium basal body; IDA:MGI.
 GO:0072372; C:primary cilium; IDA:UniProtKB.
 GO:0042384; P:cilium assembly; IMP:UniProtKB.
 GO:0008594; P:photoreceptor cell morphogenesis; ISO:MGI. 
Interpro
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical. 
Pfam
  
SMART
  
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS