CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006990
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cell wall integrity and stress response component 4 
Protein Synonyms/Alias
  
Gene Name
 WSC4 
Gene Synonyms/Alias
 YHL028W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
456FENEYQSKFYQSKYPubiquitination[1]
493RLIYTDEKGQIMSESubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
  
Sequence Annotation
 DOMAIN 27 110 WSC.
 CARBOHYD 340 340 N-linked (GlcNAc...) (Potential).
 CARBOHYD 386 386 N-linked (GlcNAc...) (Potential).
 CARBOHYD 389 389 N-linked (GlcNAc...) (Potential).
 CARBOHYD 398 398 N-linked (GlcNAc...) (Potential).
 CARBOHYD 479 479 N-linked (GlcNAc...) (Potential).
 CARBOHYD 553 553 N-linked (GlcNAc...) (Potential).
 CARBOHYD 583 583 N-linked (GlcNAc...) (Potential).  
Keyword
 Cell wall biogenesis/degradation; Complete proteome; Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 605 AA 
Protein Sequence
MQTSMVSAKV SIWLVCSVIC SSLVRATQSV CSSQNTATTD GVRNQFQSNG WCSNNCAGHQ 60
FAIVQGFMCW CSDSEPSTQT SVGDCSGTCP GYGYEDCGNA DKDLFGYIYL GQTPLSSVQS 120
VETSTESSVY VSSSSITSSS STSIVDTTTI SPTLTSTSTT PLTTASTSTT PSTDITSALP 180
TTTSTKLSTS IPTSTTSSTS TTTSTSSSTS TTVSVTSSTS TTTSTTSSTL ISTSTSSSSS 240
STPTTTSSAP ISTSTTSSTS TSTSTTSPTS SSAPTSSSNT TPTSTTFTTT SPSTAPSSTT 300
VTYTSTTASP ITSTITSVNL QTSLKYSVIT VTSVHTMDTN ISEITSRYLT MKKVITQIYS 360
STLGATPTSA VATTSASVGG RITNNNNSNT TNSNTPTNKS TEKKGYWDSP GKIAATFVVV 420
GVVCLVIICI LIYLIHHYRT RPARKAQDFE NEYQSKFYQS KYPNEVTTTT LHTPSPSSNS 480
TFSTPRLIYT DEKGQIMSES PSPRQSTYSL TAGSPPNDPS TLASPFHDPI LPRRTSTFLH 540
SPIQKQHEKM ESNVTLGEDT VLVDQRLDPS KMLNTLANDD ATNHSTISLS DNVDYSRRVL 600
RLMNE 605 
Gene Ontology
 GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0008565; F:protein transporter activity; IMP:SGD.
 GO:0045047; P:protein targeting to ER; IMP:SGD.
 GO:0006612; P:protein targeting to membrane; IMP:SGD.
 GO:0009408; P:response to heat; IGI:SGD. 
Interpro
 IPR002889; WSC_carb-bd. 
Pfam
  
SMART
  
PROSITE
 PS51212; WSC 
PRINTS