UniProt Accession

 E9PC15_HUMAN; E9PC15 

Genbank Protein ID

 AC004918; AC073878; AC099547 

Genbank Nucleotide ID

  

Protein Name

 Acylglycerol kinase, mitochondrial 

Protein Synonyms/Alias

  

Gene Name

 AGK 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
79	TDYEGQAKKLLELME	ubiquitination	[1]
171	VLQIKGEKEQPVFAM	ubiquitination	[1]
195	DAGVKVSKYWYLGPL	ubiquitination	[2]
299	NQLDPTSKEDFLNIC	ubiquitination	[1, 3]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 394 AA 

Protein Sequence

Gene Ontology

 GO:0004143; F:diacylglycerol kinase activity; IEA:InterPro.
 GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro. 

Interpro

 IPR001206; Diacylglycerol_kinase_cat_dom. 

Pfam

 PF00781; DAGK_cat 

SMART

 SM00046; DAGKc 

PROSITE

 PS50146; DAGK 

PRINTS