CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014761
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Elongation factor 1-gamma 
Protein Synonyms/Alias
 EF-1-gamma; eEF-1B gamma 
Gene Name
 Eef1g 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
294TFVLDEFKRKYSNEDacetylation[1]
434GKAVNQGKIFK****acetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Probably plays a role in anchoring the complex to other cellular components. 
Sequence Annotation
 DOMAIN 2 87 GST N-terminal.
 DOMAIN 88 216 GST C-terminal.
 DOMAIN 276 437 EF-1-gamma C-terminal.
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 147 147 N6-acetyllysine (By similarity).
 MOD_RES 434 434 N6-acetyllysine; alternate (By
 MOD_RES 434 434 N6-malonyllysine; alternate (By  
Keyword
 Acetylation; Complete proteome; Elongation factor; Protein biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 437 AA 
Protein Sequence
MAAGTLYTYP ENWRAFKALI AAQYSGAQIR VLSAPPHFHF GQTNRTPEFL RKFPAGKVPA 60
FEGDDGFCVF ESNAIAYYVS NEELRGSTPE AAAQVVQWVS FADSDIVPPA STWVFPTLGI 120
MHHNKQATEN AKEEVKRILG LLDTHLKTRT FLVGERVTLA DITVVCTLLW LYKQVLEPSF 180
RQAFPNTNRW FLTCINQPQF RAILGEVKLC EKMAQFDAKK FAESQPKKDT PRKEKGSREE 240
KQKPQTERKE EKKAAAPAPE EEMDECEQAL AAEPKAKDPF AHLPKSTFVL DEFKRKYSNE 300
DTLSVALPYF WEHFDKDGWS LWYAEYRFPE ELTQTFMSCN LITGMFQRLD KLRKNAFASV 360
ILFGTNNSSS ISGVWVFRGQ DLAFPLSPDW QVDYESYTWR KLDPGSEETQ TLVREYFSWE 420
GAFQHVGKAV NQGKIFK 437 
Gene Ontology
 GO:0005853; C:eukaryotic translation elongation factor 1 complex; IEA:InterPro.
 GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW. 
Interpro
 IPR010987; Glutathione-S-Trfase_C-like.
 IPR004045; Glutathione_S-Trfase_N.
 IPR017933; Glutathione_S_Trfase/Cl_chnl_C.
 IPR004046; GST_C.
 IPR012336; Thioredoxin-like_fold.
 IPR001662; Transl_elong_EF1_G_con. 
Pfam
 PF00647; EF1G
 PF00043; GST_C
 PF02798; GST_N 
SMART
  
PROSITE
 PS50040; EF1G_C
 PS50405; GST_CTER
 PS50404; GST_NTER 
PRINTS