CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025426
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, isoform CRA_d 
Protein Synonyms/Alias
  
Gene Name
 Sigirr 
Gene Synonyms/Alias
 AI256711; mCG_22567 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
178SDCPEDRKFVNFILKubiquitination[1]
185KFVNFILKPQLERRRubiquitination[1]
195LERRRGYKLFLEDRDubiquitination[1]
327QTRLQDDKDPMLIVRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Receptor. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 409 AA 
Protein Sequence
MAGVCDMAPN FLSPSEDQAL GLALGREVAL NCTAWVFSRP QCPQPSVQWL KDGLALGNGS 60
HFSLHEDFWV SANFSEIVSS VLVLNLTNAE DYGTFTCSVW NVSSHSFTLW RAGPAGHVAA 120
VLASLLVLVV LLLVALLYVK CRLNMLLWYQ DTYGEVEMND GKLYDAYVSY SDCPEDRKFV 180
NFILKPQLER RRGYKLFLED RDLLPRAEPS ADLLVNLSRC RRLIVVLSDA FLSRPWCSQS 240
FREGLCRLLE LTRRPIFITF EGQRREPIHP ALRLLRQHRH LVTLVLWKPG SVTPSSDFWK 300
ELQLALPRKV QYRPVEGDPQ TRLQDDKDPM LIVRGRAAQG RGMESELDPD PEGDLGVRGP 360
VFGEPPTPLQ ETRICIGESH GSEMDVSDLG SRNYSARTDF YCLVSEDDV 409 
Gene Ontology
 GO:0016020; C:membrane; IEA:Compara.
 GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IEA:Compara.
 GO:0007165; P:signal transduction; IEA:InterPro. 
Interpro
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003599; Ig_sub.
 IPR015621; IL1-receptor_fam.
 IPR000157; TIR_dom. 
Pfam
 PF01582; TIR 
SMART
 SM00409; IG 
PROSITE
 PS50835; IG_LIKE
 PS50104; TIR 
PRINTS