UniProt Accession

 KDSB_ECOLI; P04951 

Genbank Protein ID

 J02614; U00096; AP009048 

Genbank Nucleotide ID

 AAA83877.1; AAC74004.1; BAA35664.1 

Protein Name

 3-deoxy-manno-octulosonate cytidylyltransferase 

Protein Synonyms/Alias

 CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase 

Gene Name

 kdsB 

Gene Synonyms/Alias

 b0918; JW0901 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
27	PLVDINGKPMIVHVL	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity). 

Sequence Annotation

  

Keyword

 3D-structure; Complete proteome; Cytoplasm; Direct protein sequencing; Lipopolysaccharide biosynthesis; Magnesium; Nucleotidyltransferase; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 248 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0008690; F:3-deoxy-manno-octulosonate cytidylyltransferase activity; IDA:EcoCyc.
 GO:0000287; F:magnesium ion binding; IDA:EcoCyc.
 GO:0033468; P:CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process; IEA:UniProtKB-UniPathway.
 GO:0019294; P:keto-3-deoxy-D-manno-octulosonic acid biosynthetic process; IDA:EcoCyc. 

Interpro

 IPR003329; Cytidylyl_trans.
 IPR004528; KdsB. 

Pfam

 PF02348; CTP_transf_3 

SMART

  

PROSITE

  

PRINTS