CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010143
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 Asparagine--tRNA ligase 
Protein Synonyms/Alias
 Asparaginyl-tRNA synthetase; AsnRS 
Gene Name
 asnS 
Gene Synonyms/Alias
 MPN_252; MP580 
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
112ADYPLQKKEHSLEFFacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 
Functional Description
  
Sequence Annotation
  
Keyword
 Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Cytoplasm; Ligase; Nucleotide-binding; Protein biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 455 AA 
Protein Sequence
MSATAISDLF EKPAQFKNKK IKLTGWLKNK RTSANIIFLE VNDGSTLLNL QAVVKQDQPE 60
LFALAESISL ASAVSVSGTV ALTPKSKQPL ELVVKQINVL STARADYPLQ KKEHSLEFFR 120
NNAYLRVRAR TYFAIMKVRS LLSQAIFDYF FKNDFVLVHS PILTSNDCEG AGETFELKQG 180
KEFFNKTTYL TVSGQFGAEC YAQAFKKVFT FGPTFRAEKS HTSRHLSEFW MIEPEVAFAN 240
LKDLIKLIES TVKTVIKQVM QKAKQELDFL EKQFDVKLME RLKQITSTKN FHVLEYTKAL 300
EILKTAQASG QANFEVQDFN FGLDLKTEHE RFLCEQHFHN QPVFVINYPK DFKAFYMKQN 360
ADGRTVGAVD LLFPQIGEIC GGSEREGNLE KLVERCQAMQ IDTQTLNWYL DMRKWGYFAS 420
AGFGLGFDRL LAYICGLENI RDAIPFPRAH GSINY 455 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004816; F:asparagine-tRNA ligase activity; IEA:EC.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0006421; P:asparaginyl-tRNA aminoacylation; IEA:InterPro. 
Interpro
 IPR004364; aa-tRNA-synt_II.
 IPR018150; aa-tRNA-synt_II-like.
 IPR006195; aa-tRNA-synth_II.
 IPR004522; Asn-tRNA-ligase_IIb.
 IPR002312; Asp/Asn-tRNA-synth_IIb.
 IPR012340; NA-bd_OB-fold.
 IPR004365; NA-bd_OB_tRNA-helicase. 
Pfam
 PF00152; tRNA-synt_2
 PF01336; tRNA_anti 
SMART
  
PROSITE
 PS50862; AA_TRNA_LIGASE_II 
PRINTS
 PR01042; TRNASYNTHASP.