CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036522
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pacman, isoform B 
Protein Synonyms/Alias
  
Gene Name
 pcm 
Gene Synonyms/Alias
 CG3291; Dmel_CG3291 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
228VVLREEVKFGRNVKRacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 3D-structure; Complete proteome; Hydrolase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1613 AA 
Protein Sequence
MGVPKFFRYI SERYPCLSEL AREHCIPEFD NLYLDMNGIV HNCSHPDDNN IHFHLEEEQI 60
FQEIFNYVDK LFYLIKPQRL FFLSVDGVAP RAKMNQQRSR RFRTAREAEQ QEAKAAQRGE 120
LREHERFDSN CITPGTEFMV RLQEGLRAFL KTKISTDPLW QRCTVILSGQ EAPGEGEHKI 180
MDYIRYMKTQ PDYDPNTRHC LYGLDADLII LGLCTHELHF VVLREEVKFG RNVKRTSVEE 240
TRFFLLHLGL LREYLELEFD ALRTDEHKLD IAQLIDDWVL MGFLVGNDFI PHLPCLHISS 300
NALPLLYRTY IGIYPTLGGN INENGKLNLR RLQIFISALT EVELDHFKEH ADDLKYMNNK 360
SEAFDMDVGE ITESQNLDSD LGALINKSML LYDDDSEEDC SDENAVLLKE FQNYKRNFYR 420
NKFKRDPNDE LIEELCHHYV NALQWVLDYY YRGVQSWDWY YPFHYTPFIS DLKNIEQVEI 480
AFHMGTPFLP FQQLLAVLPA ASAKLLPVAY HDLMLLPTSP LAEFYPLEFE SDLNGKKHDW 540
EAVVLIPFID EGRLLAAMLP CEAQLSLEER ERNRHGPMYV YKYSTVAQGP MPAYPPLRAL 600
PVLYCTEVAK WSHEIAVNLP YSVCIELPNA ARTVFFPGFP TMQHLPFDFE LRNDRVKVFE 660
QVSRNQNIVL KPRKRQLEDT LTAVASQYLG KVIHVGWPHL VKAIVVRVAT RDQRVDSEGI 720
TLNDSRRFDS ECKALQEHFI NRMGIQFANY DVLVYVRTFA GNSTEFRDKG ALMVRDSWSS 780
SVTGYPAQGV VADLTVWERM RKNFLNVEHY FPVGSTIFLI TDPYYGSEGT VQDPRLAYTN 840
GRIQVSIMVR PEPKVNAARQ LQEERDRDYL STFQVCNLLR ISGRTLGRLS GTVWVVLGPR 900
RQKMENVTKH NIGLQLKYPR QNEERAGYCF RTNNQWYYSS LAVDLMRNYC QRYPDVIDFF 960
GDSNDRAEFV FEQDVFPNAV GHRRVEELAN WVRQQPHMKV ERISCGSKTV CRETIELLIA 1020
AVDDLRSLPV KHVKLQVKPH LLIKPNVTLP DVYRSKRPVR LFDRVVIVRT IYMVPVGTKG 1080
TVIGIHPVTD PNPVRLECVH AVDTFCKVLF DSPVPNCNNI HGIAEDRVYK VPEIALVIIK 1140
TDEEGKKQND CELPVRDPQP NQAQDEPVRA TSSRYVTAAG STSVPITMKT QISDEFVKTR 1200
SDPIARTDSY KPSSEPKPVP VPEQITNWRE RVSTPTNKPQ PAPNNWRINR SSSRQQGGSI 1260
FVAPPTKTPD AAASTASTAF TAASSATLTP LDQTLALMSV LGVGEDQSSP PLQEAVQQQR 1320
PPLLQQQRAP FPGQMPNLPK PPLFWQQEAQ KQEALQQEAQ QQEAQKKQQQ AHAQMEPERI 1380
NSQHFYRSGQ TGAALNQPPL GAPSKRQWHE WVHPRMQHAN AFHAGVNNGY QMRPKKNIAA 1440
QSTFNNNVHM HLQQPYYPNQ QQQQQQQQPL QLTEINNAPP RYSTIQDFVP IQAYRPKKLN 1500
RVQPAGRQDV DATKNPSRSP VLQQPTNETI DTKASSSLPV QSAGEQVIGL MQTLEIKQPA 1560
ASQSESDGVS TGSANAPTAT TSSQAVNRRK HRVPRIGAKF DLEYILPDSP HPT 1613 
Gene Ontology
 GO:0000932; C:cytoplasmic mRNA processing body; IDA:FlyBase.
 GO:0008409; F:5'-3' exonuclease activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0007391; P:dorsal closure; IMP:FlyBase.
 GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.
 GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.
 GO:0034428; P:nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3'; IMP:FlyBase.
 GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:FlyBase.
 GO:0010603; P:regulation of cytoplasmic mRNA processing body assembly; IMP:FlyBase.
 GO:0016246; P:RNA interference; IMP:FlyBase.
 GO:0007283; P:spermatogenesis; IMP:FlyBase.
 GO:0042060; P:wound healing; IMP:FlyBase. 
Interpro
 IPR027073; 5_3_exoribonuclease.
 IPR016494; 5_3_exoribonuclease_1.
 IPR004859; Put_53exo. 
Pfam
 PF03159; XRN_N 
SMART
  
PROSITE
  
PRINTS