GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0004708; F:MAP kinase kinase activity; IDA:MGI.
GO:0004709; F:MAP kinase kinase kinase activity; ISS:UniProtKB.
GO:0001525; P:angiogenesis; IMP:MGI.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
GO:0007252; P:I-kappaB phosphorylation; ISS:UniProtKB.
GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.
GO:0060546; P:negative regulation of necroptosis; IMP:UniProtKB.
GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IMP:UniProtKB.
GO:0001841; P:neural tube formation; IMP:MGI.
GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IGI:MGI.
GO:0046330; P:positive regulation of JNK cascade; IGI:MGI.
GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:MGI.