| Tag | Content |
|---|
| CPLM ID | CPLM-015453 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Rab11 family-interacting protein 1 |
Protein Synonyms/Alias | Rab11-FIP1; Rab-coupling protein |
Gene Name | RAB11FIP1 |
Gene Synonyms/Alias | RCP |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 541 | NNEVMMKKYSPSDPA | ubiquitination | [1] | | 565 | ELIQLVLKQKETISK | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking along the phagocytic pathway and in phagocytosis. |
Sequence Annotation | DOMAIN 5 108 C2.
DOMAIN 1211 1273 FIP-RBD.
REGION 1219 1283 Necessary for interaction with RAB4A and
MOD_RES 202 202 Phosphoserine.
MOD_RES 300 300 Phosphoserine.
MOD_RES 339 339 Phosphoserine.
MOD_RES 343 343 Phosphoserine.
MOD_RES 345 345 Phosphoserine.
MOD_RES 356 356 Phosphoserine (By similarity).
MOD_RES 357 357 Phosphoserine.
MOD_RES 382 382 Phosphoserine (By similarity).
MOD_RES 435 435 Phosphoserine.
MOD_RES 477 477 Phosphoserine.
MOD_RES 545 545 Phosphoserine.
MOD_RES 758 758 Phosphoserine.
MOD_RES 1135 1135 Phosphoserine. |
Keyword | Alternative splicing; Complete proteome; Cytoplasmic vesicle; Endosome; Membrane; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1283 AA |
Protein Sequence | MGRTRETGTE KNTSSLELEE SLPEQPETGR QEEELPRFPC KKQDYSPSSG EAQEVPFALS 60
LSSDGAVSPV GELAAGGDRD LESQAGSLVE SKARDAAEEV APPLPMGASV PSIDSMMRKL 120
EEMGLNLRKD QKKTKKRVSF SEQLFTEEAV AGAALLVEGH SSCPQELNPA WSVAGNASDG 180
EPPESPHAED SERESVTTPG PATCGAPASP ADHLLLPSQE ESFSEVPMSE ASSAKDTPLF 240
RMEGEDALVT QYQSKASDHE GLLSDPLSDL QLVSDFKSPI MADLNLSLPS IPEVASDDER 300
IDQVEDDGDQ VEDDGETAKS STLDIGALSL GLVVPCPERG KGPSGEADRL VLGEGLCDFR 360
LQAPQASVTA PSEQTTEFGI HKPHLGKSSS LDKQLPGPSG GEEEKPMGNG SPSPPPGTSL 420
DNPVPSPSPS EIFPVTHSFP SSAHSDTHHT STAESQKKAT AEGSAGRVEN FGKRKPLLQA 480
WVSPSETHPV SAQPGAGTGS AKHRLHPVKP MNAMATKVAN CSLGTATIIS ENLNNEVMMK 540
KYSPSDPAFA YAQLTHDELI QLVLKQKETI SKKEFQVREL EDYIDNLLVR VMEETPNILR 600
IPTQVGKKAG KM 612 |
Gene Ontology | GO:0005737; C:cytoplasm; IDA:HPA. GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA. GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell. GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell. GO:0015031; P:protein transport; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |