UniProt Accession

 A2ABL2_HUMAN; A2ABL2 

Genbank Protein ID

 AL662870 

Genbank Nucleotide ID

  

Protein Name

 Epithelial discoidin domain-containing receptor 1 

Protein Synonyms/Alias

  

Gene Name

 DDR1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
153	DPEGVVLKDLGPPMV	ubiquitination	[1, 2, 3]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 209 AA 

Protein Sequence

Gene Ontology

 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0060444; P:branching involved in mammary gland duct morphogenesis; IEA:Compara.
 GO:0038063; P:collagen-activated tyrosine kinase receptor signaling pathway; IEA:Compara.
 GO:0043583; P:ear development; IEA:Compara.
 GO:0007566; P:embryo implantation; IEA:Compara.
 GO:0060749; P:mammary gland alveolus development; IEA:Compara.
 GO:0008285; P:negative regulation of cell proliferation; IEA:Compara.
 GO:0018108; P:peptidyl-tyrosine phosphorylation; IEA:Compara.
 GO:0001558; P:regulation of cell growth; IEA:Compara.
 GO:0001952; P:regulation of cell-matrix adhesion; IEA:Compara.
 GO:0010715; P:regulation of extracellular matrix disassembly; IEA:Compara.
 GO:0014909; P:smooth muscle cell migration; IEA:Compara.
 GO:0061302; P:smooth muscle cell-matrix adhesion; IEA:Compara.
 GO:0044319; P:wound healing, spreading of cells; IEA:Compara. 

Interpro

 IPR000421; Coagulation_fac_5/8-C_type_dom.
 IPR008979; Galactose-bd-like. 

Pfam

 PF00754; F5_F8_type_C 

SMART

 SM00231; FA58C 

PROSITE

 PS01285; FA58C_1
 PS01286; FA58C_2
 PS50022; FA58C_3 

PRINTS