CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044391
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Anthrax toxin receptor 2 
Protein Synonyms/Alias
  
Gene Name
 ANTXR2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
294EEEPLPTKKWPTVDAubiquitination[1, 2]
322MEVRWGDKGSTEEGAubiquitination[1]
366THQPPQTKWYTPIKGubiquitination[3]
372TKWYTPIKGRLDALWubiquitination[1, 3, 4]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 411 AA 
Protein Sequence
MRLSFIVFSS QATIILPLTG DRGKISKGLE DLKRVSPVGE TYIHEGLKLA NEQIQKAGGL 60
KTSSIIIALT DGKLDGLVPS YAEKEAKISR SLGASVYCVG VLDFEQAQLE RIADSKEQVF 120
PVKGGFQALK GIINSILAQS CTEILELQPS SVCVGEEFQI VLSGRGFMLG SRNGSVLCTY 180
TVNETYTTSV KPVSVQLNSM LCPAPILNKA GETLDVSVSF NGGKSVISGS LIVTATECSN 240
GIAAIIVILV LLLLLGIGLM WWFWPLCCKV VIKDPPPPPA PAPKEEEEEP LPTKKWPTVD 300
ASYYGGRGVG GIKRMEVRWG DKGSTEEGAR LEKAKNAVVK IPEETEEPIR PRPPRPKPTH 360
QPPQTKWYTP IKGRLDALWA LLRRQYDRVS LMRPQEGDEG RCINFSRVPS Q 411 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0004872; F:receptor activity; IEA:InterPro. 
Interpro
 IPR017360; Anthrax_toxin_rcpt.
 IPR008399; Anthrax_toxin_rcpt_C.
 IPR008400; Anthrax_toxin_rcpt_extracel.
 IPR002035; VWF_A. 
Pfam
 PF05586; Ant_C
 PF05587; Anth_Ig 
SMART
 SM00327; VWA 
PROSITE
 PS50234; VWFA 
PRINTS