CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024984
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Beta adaptin 
Protein Synonyms/Alias
 Beta-adaptin Drosophila 1; LP17054p 
Gene Name
 AP-1-2beta 
Gene Synonyms/Alias
 BAD1; Bap; CG12532; Dmel_CG12532 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
319QKRPDILKHEMKVFFacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 921 AA 
Protein Sequence
MTDSKYFTTT KKGEIFELKS ELNNDKKEKK KEAVKKVIAS MTVGKDVSAL FPDVVNCMQT 60
DNLELKKLVY LYLMNYAKSQ PDMAIMAVNT FVKDCEDSNP LIRALAVRTM GCIRVDKITE 120
YLCEPLRKCL KDEDPYVRKT AAVCVAKLYD ISATMVEDQG FLDQLKDLLS DSNPMVVANA 180
VAALSEINEA SQSGQPLVEM NSVTINKLLT ALNECTEWGQ VFILDSLANY SPKDEREAQS 240
ICERITPRLA HANAAVVLSA VKVLMKLLEM LSSDSDFCAT LTKKLAPPLV TLLSSEPEVQ 300
YVALRNINLI VQKRPDILKH EMKVFFVKYN DPIYVKLEKL DIMIRLANQS NIAQVLSELK 360
EYATEVDVDF VRKAVRAIGR CAIKVEPSAE RCVSTLLDLI QTKVNYVVQE AIVVIKDIFR 420
KYPNKYESII STLCENLDTL DEPEARASMV WIIGEYAERI DNADELLDSF LEGFQDENAQ 480
VQLQLLTAVV KLFLKRPSDT QELVQHVLSL ATQDSDNPDL RDRGFIYWRL LSTDPAAAKE 540
VVLADKPLIS EETDLLEPTL LDELICHISS LASVYHKPPT AFVEGRGAGV RKSLPNRAAG 600
SAAGAEQAEN AAGSEAMVIP NQESLIGDLL SMDINAPAMP SAPAATSNVD LLGGGLDILL 660
GGPPAEAAPG GATSLLGDIF GLGGATLSVG VQIPKVTWLP AEKGKGLEIQ GTFSRRNGEV 720
FMDMTLTNKA MQPMTNFAIQ LNKNSFGLVP ASPMQAAPLP PNQSIEVSMA LGTNGPIQRM 780
EPLNNLQVAV KNNIDIFYFA CLVHGNVLFA EDGQLDKRVF LNTWKEIPAA NELQYTLSGV 840
IGTTDGIASK MTTNNIFTIA KRNVEGQDML YQSLKLTNNI WVLLELKLQP GNPEATLSLK 900
SRSVEVANII FAAYEAIIRS P 921 
Gene Ontology
 GO:0030119; C:AP-type membrane coat adaptor complex; IDA:FlyBase.
 GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
 GO:0005905; C:coated pit; IDA:FlyBase.
 GO:0008021; C:synaptic vesicle; TAS:FlyBase.
 GO:0008565; F:protein transporter activity; IC:FlyBase.
 GO:0048749; P:compound eye development; IMP:FlyBase.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0007269; P:neurotransmitter secretion; NAS:FlyBase.
 GO:0016183; P:synaptic vesicle coating; TAS:FlyBase. 
Interpro
 IPR026739; AP_beta.
 IPR016342; AP_complex_bsu_1_2_4.
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR015151; B-adaptin_app_sub_C.
 IPR012295; Beta2_adaptin/TBP_C_dom.
 IPR002553; Clathrin/coatomer_adapt-like_N.
 IPR008152; Clathrin_a/b/g-adaptin_app_Ig.
 IPR013037; Clathrin_b-adaptin_app_Ig-like.
 IPR009028; Coatomer/calthrin_app_sub_C.
 IPR013041; Coatomer/clathrin_app_Ig-like. 
Pfam
 PF01602; Adaptin_N
 PF02883; Alpha_adaptinC2
 PF09066; B2-adapt-app_C 
SMART
 SM00809; Alpha_adaptinC2
 SM01020; B2-adapt-app_C 
PROSITE
  
PRINTS