UniProt Accession

 SSRG_HUMAN; Q9UNL2; B2R7D0; D3DNK5; Q549M4 

Genbank Protein ID

 AF087907; AF110647; BT006669; AK312935; CH471052; CH471052; BC017203 

Genbank Nucleotide ID

 AAP97205.1; AAD48587.1; AAP35315.1; BAG35777.1; EAW78730.1; EAW78731.1; AAH17203.1 

Protein Name

 Translocon-associated protein subunit gamma 

Protein Synonyms/Alias

 TRAP-gamma; Signal sequence receptor subunit gamma; SSR-gamma 

Gene Name

 SSR3 

Gene Synonyms/Alias

 TRAPG 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
8	MAPKGSSKQQSEEDL	ubiquitination	[1, 2]
81	AFAYKNVKFVLKHKV	ubiquitination	[1]
85	KNVKFVLKHKVAQKR	ubiquitination	[1]
87	VKFVLKHKVAQKRED	ubiquitination	[1]
98	KREDAVSKEVTRKLS	ubiquitination	[1, 2]
103	VSKEVTRKLSEADNR	acetylation	[3]
103	VSKEVTRKLSEADNR	ubiquitination	[1]
115	DNRKMSRKEKDERIL	acetylation	[3]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 

Functional Description

 TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. 

Sequence Annotation

 MOD_RES 11 11 Phosphoserine.
 MOD_RES 105 105 Phosphoserine (By similarity).  

Keyword

 Complete proteome; Endoplasmic reticulum; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 185 AA 

Protein Sequence

Gene Ontology

 GO:0030176; C:integral to endoplasmic reticulum membrane; IEA:InterPro.
 GO:0005784; C:Sec61 translocon complex; IEA:InterPro.
 GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
 GO:0006412; P:translation; TAS:Reactome. 

Interpro

 IPR009779; TRAP-gamma. 

Pfam

 PF07074; TRAP-gamma 

SMART

  

PROSITE

  

PRINTS