CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030694
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phosphatidylserine synthase 1 
Protein Synonyms/Alias
 cDNA FLJ57481, highly similar to Phosphatidylserine synthase 1 (EC 2.7.8.-) 
Gene Name
 PTDSS1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
48TYHWASFKDIHTTTGubiquitination[1, 2, 3]
56DIHTTTGKIKRAVLQubiquitination[2, 3]
58HTTTGKIKRAVLQFTubiquitination[2, 3]
78YVRWFDPKSSFQRVAubiquitination[1, 2, 3, 4]
145YLTDTQCKRVGTQCWubiquitination[1, 2, 3, 4, 5]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [5] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 301 AA 
Protein Sequence
MHLLPNFAEC WWDQVILDIL LCNGGGIWLG MVVCRFLEMR TYHWASFKDI HTTTGKIKRA 60
VLQFTPASWT YVRWFDPKSS FQRVAGVYLF MIIWQLTELN TFFLKHIFVF QASHPLSWGR 120
ILFIGGITAP TVRQYYAYLT DTQCKRVGTQ CWVFGVIGFL EAIVCIKFGQ DLFSKTQILY 180
VVLWLLCVAF TTFLCLYGMI WYAEHYGHRE KTYSECEDGT YSPEISWHHR KGTKGSEDSP 240
PKHAGEGTWG SLFEIVSLVS HRPGRVRQII AWGAFANVGS LLTSALDMRS PVAARCVEGK 300
R 301 
Gene Ontology
 GO:0006659; P:phosphatidylserine biosynthetic process; IEA:InterPro. 
Interpro
 IPR004277; PSS. 
Pfam
 PF03034; PSS 
SMART
  
PROSITE
  
PRINTS