CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011561
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 T-SNARE affecting a late Golgi compartment protein 2 
Protein Synonyms/Alias
 Syntaxin TLG2 
Gene Name
 TLG2 
Gene Synonyms/Alias
 YOL018C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
198DLKPIRNKASAENTLubiquitination[1]
229LDIEDYSKRTLQRQQubiquitination[1]
301VELKSADKELNKATHubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 t-SNARE that functions in transport from the endosome to the late Golgi and on the endocytic pathway. 
Sequence Annotation
 DOMAIN 244 306 t-SNARE coiled-coil homology.
 MOD_RES 109 109 Phosphoserine.  
Keyword
 Coiled coil; Complete proteome; Endosome; Golgi apparatus; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 397 AA 
Protein Sequence
MFRDRTNLFL SYRRTFPHNI TFSSGKAPLG DDQDIEMGTY PMMNMSHDIS ARLTDERKNK 60
HENHSDALPP IFIDIAQDVD DYLLEVRRLS EQLAKVYRKN SLPGFEDKSH DEALIEDLSF 120
KVIQMLQKCY AVMKRLKTIY NSQFVDGKQL SREELIILDN LQKIYAEKIQ TESNKFRVLQ 180
NNYLKFLNKD DLKPIRNKAS AENTLLLDDE EEEAAREKRE GLDIEDYSKR TLQRQQQLHD 240
TSAEAYLRER DEEITQLARG VLEVSTIFRE MQDLVVDQGT IVDRIDYNLE NTVVELKSAD 300
KELNKATHYQ KRTQKCKVIL LLTLCVIALF FFVMLKPHGG GSGGRNNGSN KYNNDDNKTV 360
NNSHDDGSNT HINDEESNLP SIVEVTESEN DALDDLL 397 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0031303; C:integral to endosome membrane; IDA:SGD.
 GO:0031201; C:SNARE complex; IPI:SGD.
 GO:0005802; C:trans-Golgi network; IDA:SGD.
 GO:0005484; F:SNAP receptor activity; IDA:SGD.
 GO:0032258; P:CVT pathway; IMP:SGD.
 GO:0006897; P:endocytosis; IMP:SGD.
 GO:0006896; P:Golgi to vacuole transport; IGI:SGD.
 GO:0006675; P:mannosyl-inositol phosphorylceramide metabolic process; IMP:SGD.
 GO:0032527; P:protein exit from endoplasmic reticulum; IGI:SGD.
 GO:0006906; P:vesicle fusion; IDA:SGD. 
Interpro
 IPR006012; Syntaxin/epimorphin_CS.
 IPR010989; t-SNARE.
 IPR000727; T_SNARE_dom. 
Pfam
 PF05739; SNARE 
SMART
 SM00397; t_SNARE 
PROSITE
 PS00914; SYNTAXIN
 PS50192; T_SNARE 
PRINTS