UniProt Accession

 GNA14_MOUSE; P30677; Q8R2X9 

Genbank Protein ID

 M80631; AK160808; AK168498; CH466534; BC027015; M57616 

Genbank Nucleotide ID

 AAA83222.1; BAE36026.1; BAE40384.1; EDL41541.1; AAH27015.1; AAA63304.1 

Protein Name

 Guanine nucleotide-binding protein subunit alpha-14 

Protein Synonyms/Alias

 G alpha-14; G-protein subunit alpha-14 

Gene Name

 Gna14 

Gene Synonyms/Alias

 Gna-14 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
103	QYMCEQNKENAQIIR	ubiquitination	[1]
116	IREVEVDKVTALSRD	ubiquitination	[1]
154	YQLSDSAKYYLTDIE	ubiquitination	[1]
295	FPEYTGPKQDVKAAR	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. 

Sequence Annotation

 NP_BIND 42 49 GTP (By similarity).
 NP_BIND 176 182 GTP (By similarity).
 NP_BIND 201 205 GTP (By similarity).
 NP_BIND 270 273 GTP (By similarity).
 METAL 49 49 Magnesium (By similarity).
 METAL 182 182 Magnesium (By similarity).
 BINDING 327 327 GTP; via amide nitrogen (By similarity).  

Keyword

 Complete proteome; Direct protein sequencing; GTP-binding; Magnesium; Metal-binding; Nucleotide-binding; Reference proteome; Transducer. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 355 AA 

Protein Sequence

Gene Ontology

 GO:0005834; C:heterotrimeric G-protein complex; ISA:MGI.
 GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.
 GO:0001664; F:G-protein coupled receptor binding; IBA:RefGenome.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; ISA:MGI.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0004871; F:signal transducer activity; IBA:RefGenome.
 GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IBA:RefGenome.
 GO:0060158; P:phospholipase C-activating dopamine receptor signaling pathway; IBA:RefGenome. 

Interpro

 IPR000654; Gprotein_alpha_Q.
 IPR001019; Gprotein_alpha_su.
 IPR011025; GproteinA_insert.
 IPR027417; P-loop_NTPase. 

Pfam

 PF00503; G-alpha 

SMART

 SM00275; G_alpha 

PROSITE

  

PRINTS

 PR00318; GPROTEINA.
 PR00442; GPROTEINAQ.