CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036491
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Myosin light chain 1/3, skeletal muscle isoform 
Protein Synonyms/Alias
  
Gene Name
 Myl1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
8MAPKKDVKKPAAAPAubiquitination[1]
9APKKDVKKPAAAPAPubiquitination[1]
26APAPAPAKPKEEKIDacetylation[2]
26APAPAPAKPKEEKIDubiquitination[1]
28APAPAKPKEEKIDLSubiquitination[1]
31PAKPKEEKIDLSAIKubiquitination[1]
38KIDLSAIKIEFSKEQacetylation[2]
38KIDLSAIKIEFSKEQubiquitination[1]
43AIKIEFSKEQQEDFKacetylation[2, 3]
43AIKIEFSKEQQEDFKubiquitination[1]
50KEQQEDFKEAFLLFDacetylation[2]
50KEQQEDFKEAFLLFDubiquitination[1]
63FDRTGECKITLSQVGacetylation[2]
63FDRTGECKITLSQVGubiquitination[1]
86NPTNAEVKKVLGNPSacetylation[2]
86NPTNAEVKKVLGNPSubiquitination[1]
100SNEEMNAKKIEFEQFacetylation[2]
100SNEEMNAKKIEFEQFubiquitination[1]
101NEEMNAKKIEFEQFLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching.
 Yang L, Vaitheesvaran B, Hartil K, Robinson AJ, Hoopmann MR, Eng JK, Kurland IJ, Bruce JE.
 J Proteome Res. 2011 Sep 2;10(9):4134-49. [PMID: 21728379]
 [3] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 124 AA 
Protein Sequence
MAPKKDVKKP AAAPAPAPAP APAPAKPKEE KIDLSAIKIE FSKEQQEDFK EAFLLFDRTG 60
ECKITLSQVG DVLRALGTNP TNAEVKKVLG NPSNEEMNAK KIEFEQFLPM MQAISNNKDQ 120
GGYE 124 
Gene Ontology
 GO:0030016; C:myofibril; IEA:Compara.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0060048; P:cardiac muscle contraction; IEA:Compara. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR002048; EF_hand_dom. 
Pfam
  
SMART
  
PROSITE
 PS50222; EF_HAND_2 
PRINTS