CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034135
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 
Protein Synonyms/Alias
  
Gene Name
 Arfgef1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
218NQALQEAKQMERERHubiquitination[1]
754EFLGDNDKFNKEVMYubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1054 AA 
Protein Sequence
MYEGKKTKNM FLTRALEKIL ADKEVKKAHH SQLRKACEVA LEEIKVETEK QSPPHGEAKA 60
GSGTLPPVKS KTNFIEADKY FLPFELACQS KCPRIVSTSL DCLQKLIAYG HLTGRAPDST 120
TPGKKLIDRI IETICGCFQG PQTDEGVQLQ IIKALLTAVT SQHIEIHEGT VLQAVRTCYN 180
IYLASKNLIN QTTAKATLTQ MLNVIFARME NQALQEAKQM ERERHRQQQH LLQSPVSHHE 240
PESPHLRYLP PQTVDHINQE HEGDLEPQTH DVDKSLQDDT EPENGSDISS AENEQTEADQ 300
ATAAETLSKN DILYDGDYEE KPLDIVQSIV EEMVNIIVGD MGEGMAISAS TEGNTGTVED 360
GSDSENIQAN GIPGTPISVA YTPSLPDDRL SVSSNDTQES GNSSGPSPGA KFSHILQKDA 420
FLVFRSLCKL SMKPLSDGPP DPKSHELRSK ILSLQLLLSI LQNAGPVFRT NEMFINAIKQ 480
YLCVALSKNG VSSVPEVFEL SLSIFLTLLS NFKTHLKMQI EVFFKEIFLY ILETSTSSFD 540
HKWMVIQTLT RICADAQSVV DIYVNYDCDL NAANIFERLV NDLSKIAQGR GSQELGMSNV 600
QELSLRKKGL ECLVSILKCM VEWSKDQYVN PNSQTTLGQE KPSEQEISEV KHPETINRYG 660
SLNSLESTSS SGIGSYSTQM SGTDNPEQFE VLKQQKEIIE QGIDLFNKKP KRGIQYLQEQ 720
GMLGTTPEDI AQFLHQEERL DSTQVGEFLG DNDKFNKEVM YAYVDQHDFS GKDFVSALRL 780
FLEGFRLPGE AQKIDRLMEK FAARYLECNQ GQTLFASADT AYVLAYSIIM LTTDLHSPQV 840
KNKMTKEQYI KMNRGINDSK DLPEEYLSAI YNEIAGKKIS MKETKELTIP TKSTKQNVAS 900
EKQRRLLYNL EMEQMAKTAK ALMEAVSHVQ APFTSATHLE HVRPMFKLAW TPFLAAFSVG 960
LQDCDDTEVA SLCLEGIRCA IRIACIFSIQ LERDAYVQAL ARFTLLTVSS GITEMKQKNI 1020
DTIKTLITVA HTDGNYLGNS WHEVETLLTL QLNF 1054 
Gene Ontology
 GO:0005802; C:trans-Golgi network; IBA:RefGenome.
 GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
 GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; IBA:RefGenome. 
Interpro
 IPR000904; Sec7.
 IPR023394; SEC7_alpha_orthog. 
Pfam
 PF01369; Sec7 
SMART
 SM00222; Sec7 
PROSITE
 PS50190; SEC7 
PRINTS