CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030017
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Methyl-CpG-binding domain protein 5 
Protein Synonyms/Alias
  
Gene Name
 Mbd5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1636GLTSWPGKFIREDDVacetylation[1]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1728 AA 
Protein Sequence
MNGGKECDGG DKEGGLAAIQ VPVGWQRRVD HNGVLYISPS GSLLSCLDQV KTYLLTDGTC 60
KCGLECPLIL PKVFNFDPGA AVKQRTAEDV KADDDVTKLC IHKRKIIAVA TLHQSMEAPH 120
PSLVLTSPGG GTNATPVVPS RAATPRSVRN KSHEGITNSV MPECKNPFKL MTGSSNAMGR 180
LYMQDLPGSQ QQELHPVYPR QRLGSSEHGQ KSPFRGSHGG LPSPASSGSQ IYGDGSISPR 240
TDPLGSPDVF TRNNPGFHGA PNSSPIHLNR TPLSPPSVML HGSPVQSSCA MAGRTNIPLS 300
PTLTTKSPVM KKPMCNFSTN MEIPRAMFHH KPPQGPPPPP PPSCALQKKP LTSEKDPLGI 360
LDPIPSKPVN QNPIIINPTS FHSNVHSQVP VMNVSMPPAV VPLPSNLPLP TVKPGHMNHG 420
SHVQRIQHSA STSLSPSPVT SPVHMMGTGI GRIEASPQRS RSSSTSSDHG NFMMPPVGPQ 480
ATCSGIKVPP RSPRSTIGSP RPSMPSSPST KSDGHHQYKD IPNPLIAGMS NVLNTPSSAA 540
FPTAPAGNGS VKSQPGLLGM PLNQILNQHN AASFPASSLL SAAAKAQLAN QNKLAGNNSS 600
SSNNSGAVAS SGNTEGHSTL NTMFPPTANM LLPTGEGQSG RAALRDKLMS QQKDSLRKRK 660
QPPTTVLSLL RQSQMDSSAA PKPGPDLLRK HGQGSFPISS MSQLLQSMSC QSSHLSSNST 720
PGCGGSNTAL PCSANQLHFP DPNMNSTVLQ NSLTQSIPLR GEAVHCHNAN TNFVHSNSPV 780
PNHHLAGLIN QIQASGNCGM LSQSGMALGN SLHPNPPQSR ISTSSTPVIP NSIVSSYNQT 840
SSEAGGSSLP SSIAIAGSNH PAITKTTSVL QDGVIVTTAA GNPLQSQLPI GSDFPFVGQE 900
HALHFPSNST ANNHLPHPLN PSLLSSLPIS LPVNQQHLLN QNLLNILQPS AGEGKSEINL 960
HPLGFLNPNV NAALAFLSGD VDGQVLQPVH FQLLAALLQN QAQAAAMLPL PSFNLTISDL 1020
LQPQNTPLPL LTQMTAPPDR LPSNQSDNSR ADTLLGSPLG NPLAGSDTTF NPLLLPAVTG 1080
ASGLMALNPQ LLGGVLNSAS ANTAIHPEVS IATSSQATTT TTTTSSAVAA LTVSTLGGTA 1140
VVSMAETLLN ISNNAGNPPG PAKLNSNSMV PQLLNPLLGT GLLGDISSIN NSLNNHQLTH 1200
LQSLLNSNQM FPPNQQPQQH LLQGHQNLQA FQGQPTVPCP ANNNPMACLF QNFQVRMQGD 1260
AALLNKRIST QPGLTTLPEN PNLALPHFQD TPCELQPRID LGQPMKDGLV MGGQGDASVD 1320
AIYKAVVDAA SKGMQVVITT AVNSTTQISP IPALSAMSAF TASIGDPLNL SSAVSAVIHG 1380
RNMGGVDHDG RLRNARGARL PKNIDHGKNS SEGDGFECFK SASCHTSRKQ WDGEQSPRGE 1440
RNRWKYEEFL DHPGHIHSSP CHERPNNVST LPFLAGEQHP ILLPPRNCQG DKILEENFRY 1500
NNYKRTMMSF KERLESTVER CTHINGNRPR QSRGFGELLG TAKQDLVLEG QSPGSSNSLE 1560
SSLVKDYIHY NGDFNAKTIN GCVPSPSDAK SISSEDDLRN PDSPSSHELI HYRPRTFNVG 1620
DLVWGQIKGL TSWPGKFIRE DDVHNSCQQS PEEGKVEPEK LKTLTEGLEA YSRVRKRSRK 1680
SGKLNNHLEA AIHEAMSELD KMSGTVHQIP QGDRQMRPPK PKRRKISR 1728 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0003682; F:chromatin binding; IEA:Compara.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0042593; P:glucose homeostasis; IMP:MGI.
 GO:0060399; P:positive regulation of growth hormone receptor signaling pathway; IMP:MGI.
 GO:0040014; P:regulation of multicellular organism growth; IMP:MGI. 
Interpro
 IPR001739; Methyl_CpG_DNA-bd. 
Pfam
  
SMART
  
PROSITE
 PS50982; MBD 
PRINTS