| Tag | Content |
|---|
| CPLM ID | CPLM-022573 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | KAT8 regulatory NSL complex subunit 3 |
Protein Synonyms/Alias | NSL complex protein NSL3; Non-specific lethal 3 homolog; Serum inhibited-related protein; Testis development protein PRTD |
Gene Name | KANSL3 |
Gene Synonyms/Alias | KIAA1310; NSL3; PRTD; SI1 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 95 | MPLYDNQKARSVMNE | ubiquitination | [1] | | 236 | MLVSSNTKTGAAGAE | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. |
Sequence Annotation | MOD_RES 523 523 Phosphoserine.
MOD_RES 540 540 Phosphoserine. |
Keyword | Alternative splicing; Chromatin regulator; Complete proteome; Nucleus; Phosphoprotein; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 904 AA |
Protein Sequence | MAHRGGERDF QTSARRMGTS LLFQLSVHER ELDLVFLDHS YAKPWSAHPD ASSARPTRML 60
FVTPRRQHES TIESDVPIDV ETVTSTPMPL YDNQKARSVM NECERHVIFA RTDADAPPPP 120
EDWEEHVNRT GWTMAQNKLF NKILKALQSD RLARLANEGA CNEPVLRRVA VDKCARRVRQ 180
ALASVSWDTK LIQWLHTTLV ETLSLPMLAA YLDALQTLKG KIPTLIDRML VSSNTKTGAA 240
GAEALSLLLK RPWDPAVGVL SHNKPSKLPG SPLILIASSG PSSSVFPTSR RHRFWQSQLS 300
CLGKVIPVAT HLLNNGSGVG VLQCLEHMIG AVRSKVLEIH SHFPHKPIIL IGWNTGALVA 360
CHVSVMEYVT AVVCLGFPLL TVDGPRGDVD DPLLDMKTPV LFVIGQNSLQ CHPEAMEDFR 420
EKIRAENSLV VVGGADDNLR ISKAKKKSEG LTQSMVDRCI QDEIVDFLTG VLTRAEGHMG 480
SEPRDQDAEK KKKPRDVARR DLAFEVPERG SRPASPAAKL PASPSGSEDL SSVSSSPTSS 540
PKTKVTTVTS AQKSSQIGSS QLLKRHVQRT EAVLTHKQAQ AQFAAFLKQN MLVRKALPPG 600
TSSCLFVPIS SEPPEEGEKE DLRVQLKRHH PSSPLPGSKT SKRPKIKVSL ISQGDTAGGP 660
CAPSQGSAPE AAGGKPITMT LGQASAGAKE LTGLLTTAKS SSSEGGVSAS PVPSVVSSST 720
APSALHTLQS RLVATSPGSS LPGATSASSL LQGLSFSLQD ISSKTSGLPA NPSPGPAPQA 780
TSVKLPTPMQ SLGAITTGTS TIVRTIPVAT TLSSLGATPG GKPTAIHQLL TNGGLAKLAS 840
SLPGLAQISN QASGLKVPTT ITLTLRGQPS RITTLSPMGS GAAPSEESSS QVLPSSSQRL 900
PPAP 904 |
Gene Ontology | GO:0000123; C:histone acetyltransferase complex; IDA:UniProtKB. GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB. GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB. GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |