CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025815
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transporter 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
52GPDGAPAKGDGPVGLubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Membrane; Symport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 644 AA 
Protein Sequence
PPPPVRRRDP GPAVRPAGAM AKKSAENGIY SVSGDEKKGP LIAPGPDGAP AKGDGPVGLG 60
TPGGRLAVPP RETWTRQMDF IMSCVGFAVG LGNVWRFPYL CYKNGGGVFL IPYVLIALVG 120
GIPIFFLEIS LGQFMKAGSI NVWNICPLFK GLGYASMVIV FYCNTYYIMV LAWGFYYLVK 180
SFTTTLPWAT CGHTWNTPDC VEIFRHEDCA NASLANLTCD QLADRRSPVI EFWENKVLRL 240
SGGLEVPGAL NWEVTLCLLA CWVLVYFCVW KGVKSTGKIV YFTATFPYVV LVVLLVRGVL 300
LPGALDGIIY YLKPDWSKLG SPQVWIDAGT QIFFSYAIGL GALTALGSYN RFNNNCYNGT 360
SFFAGFVVFS ILGFMAAEQG VHISKVAESG PGLAFIAYPR AVTLMPVAPL WAALFFFMLL 420
LLGLDSQFVG VEGFITGLLD LLPASYYFRF QREISVALCC ALCFVIDLSM VTDGGMYVFQ 480
LFDYYSASGT TLLWQAFWEC VVVAWVYGAD RFMDDIACMI GYRPCPWMKW CWSFFTPLVC 540
MGIFIFNVVY YEPLVYNNTY VYPWWGEAMG WAFALSSMLC VPLHLLGCLL RAKGTMAERW 600
QHLTQPIWGL HHLEYRAQDA DVRGLTTLTP VSESSKVVVV ESVM 644 
Gene Ontology
 GO:0005887; C:integral to plasma membrane; IEA:InterPro.
 GO:0005309; F:creatine:sodium symporter activity; IEA:InterPro.
 GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. 
Interpro
 IPR000175; Na/ntran_symport.
 IPR002984; Na/ntran_symport_creatine. 
Pfam
 PF00209; SNF 
SMART
  
PROSITE
 PS00610; NA_NEUROTRAN_SYMP_1
 PS00754; NA_NEUROTRAN_SYMP_2
 PS50267; NA_NEUROTRAN_SYMP_3 
PRINTS
 PR01199; CRTTRANSPORT.
 PR00176; NANEUSMPORT.