UniProt Accession

 E0IY85_ECOLW; E0IY85 

Genbank Protein ID

 CP002185; CP002967; AEDF01000004 

Genbank Nucleotide ID

 ADT75852.1; AFH12027.1; EFN39212.1 

Protein Name

 DNA-binding response regulator in two-component regulatory system with RcsC and RcsD 

Protein Synonyms/Alias

 Transcriptional regulator RcsB; Two component transcriptional regulator, LuxR family 

Gene Name

 rcsB 

Gene Synonyms/Alias

 ECW_m2419; WFL_11835; EschWDRAFT_1292 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain ATCC 9637 / CCM 2024 / DSM 1116 / NCIMB 866 

NCBI Taxa ID

 566546 

Lysine Modification

Position	Peptide	Type	References
63	DLSMPGDKYGDGITL	acetylation	[1]
72	GDGITLIKYIKRHFP	acetylation	[1]
118	GAPTDLPKALAALQK	acetylation	[1]
125	KALAALQKGKKFTPE	acetylation	[1]
127	LAALQKGKKFTPESV	acetylation	[1]
128	AALQKGKKFTPESVS	acetylation	[1]
140	SVSRLLEKISAGGYG	acetylation	[1]
149	SAGGYGDKRLSPKES	acetylation	[1]
154	GDKRLSPKESEVLRL	acetylation	[1]
173	FLVTEIAKKLNRSIK	acetylation	[1]
180	KKLNRSIKTISSQKK	acetylation	[1]
186	IKTISSQKKSAMMKL	acetylation	[1]

Reference

 [1] Acetylation of the Response Regulator RcsB Controls Transcription from a Small RNA Promoter.
 Hu LI, Chi BK, Kuhn ML, Filippova EV, Walker-Peddakotla AJ, Bäsell K, Becher D, Anderson WF, Antelmann H, Wolfe AJ.
 J Bacteriol. 2013 Jul 12;. [PMID: 23852870] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; DNA-binding; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 216 AA 

Protein Sequence

Gene Ontology

 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0035556; P:intracellular signal transduction; IEA:GOC.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR011006; CheY-like_superfamily.
 IPR016032; Sig_transdc_resp-reg_C-effctor.
 IPR001789; Sig_transdc_resp-reg_receiver.
 IPR000792; Tscrpt_reg_LuxR_C.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

 PF00196; GerE
 PF00072; Response_reg 

SMART

 SM00421; HTH_LUXR
 SM00448; REC 

PROSITE

 PS00622; HTH_LUXR_1
 PS50043; HTH_LUXR_2
 PS50110; RESPONSE_REGULATORY 

PRINTS

 PR00038; HTHLUXR.