| Tag | Content |
|---|
| CPLM ID | CPLM-020870 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Solute carrier family 52, riboflavin transporter, member 2 |
Protein Synonyms/Alias | Porcine endogenous retrovirus A receptor 2 homolog; PERV-A receptor 2 homolog; Protein GPR172B; Riboflavin transporter 1; mRFT1 |
Gene Name | Slc52a2 |
Gene Synonyms/Alias | Gpr172b; Rft1 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 272 | IVSSPDPKAHQLFSS | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Riboflavin transporter. Riboflavin transport is Na(+)- independent but moderately pH-sensitive. Activity is strongly inhibited by riboflavin analogs, such as lumiflavin. Weakly inhibited by flavin adenine dinucleotide (FAD). In case of infection by retroviruses, acts as a cell receptor to retroviral envelopes similar to the porcine endogenous retrovirus (PERV-A) (By similarity). |
Sequence Annotation | CARBOHYD 178 178 N-linked (GlcNAc...) (Potential). |
Keyword | Alternative splicing; Cell membrane; Complete proteome; Glycoprotein; Membrane; Receptor; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 450 AA |
Protein Sequence | MAAPPLGRLV LTHLLVALFG MGSWAAVNGI WVELPVVVKE LPEGWSLPSY LSVLVALGNL 60
GLLLVTLWRR LARGKGEQVP IRVVQGLGIV GTGLLASLWN HVAPVAGKPY SVAFLTLAFV 120
LALACCASNV TFLPFLSHLP PPFLRSFFLG QGLSALLPCV LALGQGVGRL ECLHVPANRT 180
TGPPIEVSPI NFPERFSATT FFWVLTALLG TSAAAFQGLL LLLPSPTSEP TTGTGLRVET 240
PGTEEEEEEE EASPLQEPPG QVAGIVSSPD PKAHQLFSSR SACLLGLLAI TNALTNGVLP 300
AVQSFSCLPY GRLAYHLAVV LGSCANPLAC FLAMAVLCRS LAGLCGLSLL GMLLGSYLMT 360
LAALSPCPPL VGTSAGVVLV VLSWVLCAGT FSYIKVAISS MLHSGGRPAL LAAGVAIQVG 420
SLLGAVAMFP PTSIYRVFRS GKDCVDQCGL 450 |
Gene Ontology | GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. GO:0032217; F:riboflavin transporter activity; ISS:UniProtKB. |
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Pfam | |
SMART | |
PROSITE | |
PRINTS | |