| Tag | Content |
|---|
| CPLM ID | CPLM-016007 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | DDB1- and CUL4-associated factor 5 |
Protein Synonyms/Alias | WD repeat-containing protein 22 |
Gene Name | Dcaf5 |
Gene Synonyms/Alias | Kiaa1824; Wdr22 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 219 | VGLWDIRKPQSSLLR | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity). |
Sequence Annotation | REPEAT 51 91 WD 1.
REPEAT 99 139 WD 2.
REPEAT 140 180 WD 3.
REPEAT 185 225 WD 4.
REPEAT 277 317 WD 5.
REPEAT 331 370 WD 6.
MOD_RES 626 626 Phosphoserine.
MOD_RES 628 628 Phosphoserine.
MOD_RES 631 631 Phosphoserine.
MOD_RES 632 632 Phosphoserine. |
Keyword | Complete proteome; Phosphoprotein; Reference proteome; Repeat; Ubl conjugation pathway; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 946 AA |
Protein Sequence | MKRRAGLGGS MRSVVGFLSQ RGLHGDPLLT QDFQRRRLRG CRNLYKKDLL GHFGCVNAIE 60
FSNNGGQWLV SGGDDRRVLL WHMEQAIHSR VKPIQLKGEH HSNIFCLAFN SGNTKVFSGG 120
NDEQVILHDV ESSETLDVFA HEDAVYGLSV SPVNDNIFAS SSDDGRVLIW DIRESPHGEP 180
FCLANYPSAF HSVMFNPVEP RLLATANSKE GVGLWDIRKP QSSLLRYGGN LSLQSAMSVR 240
FNSNGTQLLA LRRRLPPVLY DIHSRLPVFQ FDNQGYFNSC TMKSCCFAGD RDQYILSGSD 300
DFNLYMWKIP ADPEAGGIGR VVNGAFMVLK GHRSIVNQVR FNPHTYMICS SGVEKIIKIW 360
SPYKQPGCTG DLDGRIEDDS RCLYTHEEYI SLVLNSGSGL SHDYANQSVQ EDPRMMAFFD 420
SLVRREIEGW SSDSDSDLSE STILQLHAGV SERSGYTDSE SSASLPRSPP PTVDESADNA 480
FHLGPLRVTT TNAVASTPAT PTCEDASSRQ QRLSALRRYQ DKRLLALSNE SDSEENVCEA 540
ELDTDLFPRP RSPSPEDGSS SPSSSTSSED EEELNQRRAT TRQRNAMRRR QKTARDERPT 600
GPAKSTNTYI GEDNYDYPQI KVDDLSPSPD SSPERSASTL DVQPSRAPPA ANMESVERKI 660
YKAYKWLRCS YISYSNNKDG ETSLMAEEAD EGRAGTSHKD NPTPSSSKEA CLTATAQRDQ 720
DLPSEGCSSD ACKEGTSAGN PNSGAGHEHS SHPWAEVPEG TSQDTNNSGP LEHSFETKKL 780
NGKALSKALS SRAEEPPASP GPKASGSTLN SASGNCPRTQ SDDSEERSLD TVCANHNNGR 840
LHPRPLHPHN NGQSSGELET VACSSPGHLD TDHDSPSLTG TFLHKDCCGS EMACETPSAG 900
MREDPPDPSG LDSSKVVHGQ SGLKRHRIEL EDTESENSSS EKKLKT 946 |
Gene Ontology | GO:0080008; C:Cul4-RING ubiquitin ligase complex; ISS:UniProtKB. GO:0005739; C:mitochondrion; IDA:MGI. GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |