CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017776
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 G2 and S phase-expressed protein 1 
Protein Synonyms/Alias
 GTSE-1; Protein B99 
Gene Name
 Gtse1 
Gene Synonyms/Alias
 B99 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
289RSLPIPGKLGLKKTLacetylation[1]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
 May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression. 
Sequence Annotation
 MOD_RES 73 73 Phosphoserine (By similarity).
 MOD_RES 139 139 Phosphoserine (By similarity).
 MOD_RES 153 153 Phosphoserine (By similarity).
 MOD_RES 191 191 Phosphoserine (By similarity).
 MOD_RES 476 476 Phosphoserine.
 MOD_RES 493 493 Phosphoserine (By similarity).
 MOD_RES 509 509 Phosphoserine (By similarity).
 MOD_RES 514 514 Phosphoserine (By similarity).
 MOD_RES 518 518 Phosphothreonine (By similarity).
 MOD_RES 521 521 Phosphoserine (By similarity).
 MOD_RES 541 541 Phosphoserine (By similarity).
 MOD_RES 582 582 Phosphoserine (By similarity).
 MOD_RES 599 599 Phosphoserine (By similarity).
 MOD_RES 696 696 Phosphothreonine (By similarity).
 MOD_RES 720 720 Phosphoserine (By similarity).
 MOD_RES 726 726 Phosphoserine (By similarity).
 MOD_RES 736 736 Phosphoserine (By similarity).  
Keyword
 Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 741 AA 
Protein Sequence
MDAGSKKEDF LLLEDEKFDF DLSLSSSSTN EDDEVFFGPV GHKERCIAAS LDLNRRVPGQ 60
PLAPGSGSPC TLSPLTGEKF VEVYKEAHLL ALQIESHSRR EVAQAATPQN PVNQGKETFV 120
QDSQLKVSLF EKEQKRDRSP MSLKRETFCL PSSRVQPPMG EPQLLASPGL LSSPVSAGPA 180
QTQSNQGLPC SSQPLPRESS TSQPPSQAGP QKRITSKLQP PRALPVRGRN LHLATEKLKK 240
EVPASIQRTK LVNEKGSQSD VLQDKPSTAP DAASREGHPG KRSLPIPGKL GLKKTLLKPP 300
GYTGNLTRKS STSGSASSLE SGVYRSSVAG KAKSSEQRSS IPASGSQRRT STSKSGRIGP 360
AASRQALPAA PARVFGRQAN KADAAQTVAE QPKVPTLSPL TQQPQTPEQR GPRLDPDTET 420
PQLNKTVSIK RRDSYLSCKT EAVSTTTNPF KVPQFSVGES PGGVTPKFSR THRLQSWTPA 480
SRVVSSTPVR RSSGTTPQGL PGSMRTPLST RRMSVLPTPA SRRLSSLPLM APQSMPRALV 540
SPLCVPARRL SSEPRRRSTV RAELTQESSG SGSGGQAQGL SSDESSSPPS SVPQALNFSP 600
EKSASPPPQG SSTGAAQGEA EPPEDTLPSE VHGGGCSHTP SEGLLLDLKL DQLTITPEAG 660
GRDLADCPLI DFSNTPESNT ALGPSSWPLI DLIMNTPDMG RNDVGKPAKA ELGQLIDLGS 720
PLIQLSPEAD KENVDSPLLK F 741 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW. 
Interpro
 IPR026657; DDA3/GTSE-1.
 IPR026659; GTSE1. 
Pfam
  
SMART
  
PROSITE
  
PRINTS