UniProt Accession

 HDHD2_RAT; Q6AYR6 

Genbank Protein ID

 BC078941 

Genbank Nucleotide ID

 AAH78941.1 

Protein Name

 Haloacid dehalogenase-like hydrolase domain-containing protein 2 

Protein Synonyms/Alias

  

Gene Name

 Hdhd2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
50	RFVTNTTKESKRDLL	acetylation	[1]
182	VVVGKPEKTFFLEAL	acetylation	[1]
229	LVKTGKYKAADEEKI	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

  

Sequence Annotation

 REGION 13 15 Substrate binding (By similarity).
 REGION 46 47 Substrate binding (By similarity).
 METAL 13 13 Magnesium (By similarity).
 METAL 15 15 Magnesium; via carbonyl oxygen (By
 METAL 204 204 Magnesium (By similarity).
 BINDING 179 179 Substrate (By similarity).  

Keyword

 Coiled coil; Complete proteome; Magnesium; Metal-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 259 AA 

Protein Sequence

Gene Ontology

 GO:0016787; F:hydrolase activity; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. 

Interpro

 IPR023214; HAD-like_dom.
 IPR006357; HAD-SF_hydro_IIA.
 IPR006355; HAD-SF_hydro_IIA_hyp2.
 IPR023215; NPhePase-like_dom. 

Pfam

 PF13344; Hydrolase_6 

SMART

  

PROSITE

  

PRINTS