CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000398
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Centrin-3 
Protein Synonyms/Alias
  
Gene Name
 CETN3 
Gene Synonyms/Alias
 CEN3 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
108EEILKAFKLFDDDDSubiquitination[1]
117FDDDDSGKISLRNLRubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
 Plays a fundamental role in microtubule-organizing center structure and function. 
Sequence Annotation
 DOMAIN 25 60 EF-hand 1.
 DOMAIN 61 96 EF-hand 2.
 DOMAIN 98 133 EF-hand 3.
 DOMAIN 134 167 EF-hand 4.  
Keyword
 Calcium; Cell cycle; Cell division; Complete proteome; Cytoplasm; Cytoskeleton; Metal-binding; Mitosis; Polymorphism; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 167 AA 
Protein Sequence
MSLALRSELV VDKTKRKKRR ELSEEQKQEI KDAFELFDTD KDEAIDYHEL KVAMRALGFD 60
VKKADVLKIL KDYDREATGK ITFEDFNEVV TDWILERDPH EEILKAFKLF DDDDSGKISL 120
RNLRRVAREL GENMSDEELR AMIEEFDKDG DGEINQEEFI AIMTGDI 167 
Gene Ontology
 GO:0005814; C:centriole; TAS:ProtInc.
 GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.
 GO:0005932; C:microtubule basal body; IEA:Compara.
 GO:0032391; C:photoreceptor connecting cilium; IEA:Compara.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0007098; P:centrosome cycle; TAS:ProtInc.
 GO:0007067; P:mitosis; IEA:UniProtKB-KW. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom. 
Pfam
 PF13499; EF_hand_5 
SMART
 SM00054; EFh 
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 
PRINTS