| Tag | Content |
|---|
| CPLM ID | CPLM-014745 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 57 |
Protein Synonyms/Alias | Zinc finger protein 424 |
Gene Name | ZNF57 |
Gene Synonyms/Alias | ZNF424 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 67 | MYGQEKSKEQTIPNF | ubiquitination | [1] | | 98 | YGTEDHHKNLRNHMV | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 4 76 KRAB.
ZN_FING 140 162 C2H2-type 1.
ZN_FING 196 218 C2H2-type 2; degenerate.
ZN_FING 224 246 C2H2-type 3.
ZN_FING 252 274 C2H2-type 4.
ZN_FING 280 302 C2H2-type 5.
ZN_FING 308 330 C2H2-type 6.
ZN_FING 336 358 C2H2-type 7.
ZN_FING 364 386 C2H2-type 8.
ZN_FING 392 414 C2H2-type 9.
ZN_FING 420 442 C2H2-type 10.
ZN_FING 448 470 C2H2-type 11.
ZN_FING 476 498 C2H2-type 12.
ZN_FING 504 526 C2H2-type 13. |
Keyword | Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 555 AA |
Protein Sequence | MDSVVFEDVA VDFTLEEWAL LDSAQRDLYR DVMLETFRNL ASVDDGTQFK ANGSVSLQDM 60
YGQEKSKEQT IPNFTGNNSC AYTLEKNCEG YGTEDHHKNL RNHMVDRFCT HNEGNQYGEA 120
IHQMPDLTLH KKVSAGEKPY ECTKCRTVFT HLSSLKRHVK SHCGRKAPPG EECKQACICP 180
SHLHSHGRTD TEEKPYKCQA CGQTFQHPRY LSHHVKTHTA EKTYKCEQCR MAFNGFASFT 240
RHVRTHTKDR PYKCQECGRA FIYPSTFQRH MTTHTGEKPY KCQHCGKAFT YPQAFQRHEK 300
THTGEKPYEC KQCGKTFSWS ETLRVHMRIH TGDKLYKCEH CGKAFTSSRS FQGHLRTHTG 360
EKPYECKQCG KAFTWSSTFR EHVRIHTQEQ LYKCEQCGKA FTSSRSFRGH LRTHTGEKPY 420
ECKQCGKTFT WSSTFREHVR IHTQEQLHKC EHCGKAFTSS RAFQGHLRMH TGEKPYECKQ 480
CGKTFTWSST LHNHVRMHTG EKPHKCKQCG MSFKWHSSFR NHLRMHTGQK SHECQSYSKA 540
FSCQVILSKT SESTH 555 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |