UniProt Accession

 ACPM_HUMAN; O14561; B2R4M1; Q9UNV1 

Genbank Protein ID

 AF087660; AK311877; AC002400; CH471145; BC058920 

Genbank Nucleotide ID

 AAD23566.1; BAG34818.1; AAC05814.1; EAW55816.1; AAH58920.1 

Protein Name

 Acyl carrier protein, mitochondrial 

Protein Synonyms/Alias

 ACP; CI-SDAP; NADH-ubiquinone oxidoreductase 9.6 kDa subunit 

Gene Name

 NDUFAB1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
88	DRVLYVLKLYDKIDP	ubiquitination	[1, 2]
92	YVLKLYDKIDPEKLS	acetylation	[3]
97	YDKIDPEKLSVNSHF	ubiquitination	[1, 2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [3] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861] 

Functional Description

 Carrier of the growing fatty acid chain in fatty acid biosynthesis in mitochondria. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (By similarity). 

Sequence Annotation

 MOD_RES 112 112 O-(pantetheine 4'-phosphoryl)serine  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; Electron transport; Fatty acid biosynthesis; Fatty acid metabolism; Lipid biosynthesis; Lipid metabolism; Mitochondrion; Phosphopantetheine; Reference proteome; Respiratory chain; Transit peptide; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 156 AA 

Protein Sequence

Gene Ontology

 GO:0005759; C:mitochondrial matrix; ISS:UniProtKB.
 GO:0005747; C:mitochondrial respiratory chain complex I; IDA:UniProtKB.
 GO:0000036; F:ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process; NAS:UniProtKB.
 GO:0005509; F:calcium ion binding; NAS:UniProtKB.
 GO:0005504; F:fatty acid binding; ISS:UniProtKB.
 GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
 GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
 GO:0009249; P:protein lipoylation; IMP:UniProtKB. 

Interpro

 IPR003231; Acyl_carrier.
 IPR009081; Acyl_carrier_prot-like.
 IPR006162; PPantetheine_attach_site. 

Pfam

 PF00550; PP-binding 

SMART

  

PROSITE

 PS50075; ACP_DOMAIN
 PS00012; PHOSPHOPANTETHEINE 

PRINTS