CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040797
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 YTH domain family protein 1 
Protein Synonyms/Alias
  
Gene Name
 YTHDF1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
141EQGMVGLKIGDVSSSubiquitination[1]
320ESHPVLEKLKAAHSYubiquitination[1, 2]
322HPVLEKLKAAHSYNPubiquitination[1]
369CSTEHGNKRLDSAFRubiquitination[1]
450RLENNDNKPVTNSRDubiquitination[1]
491DDFAHYEKRQEEEEVubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 509 AA 
Protein Sequence
MSDPYLSSYY PPSIGFPYSL NEAPWSTAGD PPIPYLTTYG QLSNGDHHFM HDAVFGQPGG 60
LGNNIYQHRF NFFPENPAFS AWGTSGSQGQ QTQSSAYGSS YTYPPSSLGG TVVDGQPGFH 120
SDTLSKAPGM NSLEQGMVGL KIGDVSSSAV KTVGSVVSSV ALTGVLSGNG GTNVNMPVSK 180
PTSWAAIASK PAKPQPKMKT KSGPVMGGGL PPPPIKHNMD IGTWDNKGPV PKAPVPQQAP 240
SPQAAPQPQQ VAQPLPAQPP ALAQPQYQSP QQPPQTRWVA PRNRNAAFGQ SGGAGSDSNS 300
PGNVQPNSAP SVESHPVLEK LKAAHSYNPK EFEWNLKSGR VFIIKSYSED DIHRSIKYSI 360
WCSTEHGNKR LDSAFRCMSS KGPVYLLFSV NGSGHFCGVA EMKSPVDYGT SAGVWSQDKW 420
KGKFDVQWIF VKDVPNNQLR HIRLENNDNK PVTNSRDTQE VPLEKAKQVL KIISSYKHTT 480
SIFDDFAHYE KRQEEEEVVR KERQSRNKQ 509 
Gene Ontology
  
Interpro
 IPR007275; YTH_domain. 
Pfam
 PF04146; YTH 
SMART
  
PROSITE
 PS50882; YTH 
PRINTS